• How brain paralyzes muscles while you sleep
    150 replies, posted
[quote] The chemical systems work together to paralyze skeletal muscles during rapid eye movement (REM) sleep, according to a study published in the July 11 issue of the Journal of Neuroscience. The finding may help scientists better understand and treat disorders, including narcolepsy, tooth grinding, and REM sleep behavior disorder. In a series of experiments, University of Toronto neuroscientists Patricia L. Brooks and John H. Peever found that the neurotransmitters gamma-aminobutyric acid (GABA) and glycine caused REM sleep paralysis in rats by “switching off” the specialized cells in the brain that allow muscles to be active. This finding reversed earlier beliefs that glycine was a lone inhibitor of these motor neurons. “The study’s findings are relevant to anyone who has ever watched a sleeping pet twitch, gotten kicked by a bed partner, or has known someone with the sleep disorder narcolepsy,” says Dennis J. McGinty, a behavioral neuroscientist and sleep researcher at the University of California, Los Angeles, who was not involved in the study. “By identifying the neurotransmitters and receptors involved in sleep-related paralysis, this study points us to possible molecular targets for developing treatments for sleep-related motor disorders, which can often be debilitating,” McGinty says. The researchers measured electrical activity in the facial muscles responsible for chewing of sleeping rats. Brain cells called trigeminal motor neurons communicate the brain’s message to move to these muscles. Previous research suggested neurotransmitter receptors called ionotropic GABAA/glycine receptors in the motor neurons caused REM sleep paralysis. However, when the researchers blocked these receptors, REM sleep paralysis still occurred. The researchers found that to prevent REM sleep paralysis, they had to block both the ionotropic receptors and metabotropic GABAB receptors, a different receptor system. In other words, when the motor cells were cut off from all sources of GABA and glycine, the paralysis did not occur, allowing the rats to exhibit high levels of muscle activity when their muscles should have been inactive. The data suggest the two neurotransmitters must both be present together to maintain motor control during sleep, rather than working separately. The finding could be especially helpful for those with REM sleep disorder, a disease that causes people to act out their dreams. This can cause serious injuries to patients and others around them. It is also often an early indicator of neurodegenerative diseases, such as Parkinson’s. “Understanding the precise mechanism behind these chemicals’ role in REM sleep disorder is particularly important because about 80 percent of people who have it eventually develop a neurodegenerative disease, such as Parkinson’s disease,” study author Peever adds. “REM sleep behavior disorder could be an early marker of these diseases, and curing it may help prevent or even stop their development,” he says. This study was funded by the Canadian Institutes of Health Research and the National Science and Engineering Research Council of Canada.[/quote] [url]http://www.futurity.org/top-stories/how-brain-paralyzes-muscles-while-you-sleep/[/url]
I always run a marathon while sleeping
[QUOTE=DrLuke;36731398]I always run a marathon while sleeping[/QUOTE] I thought I was the only one who did this!
You can learn to control that REM, keeping you mind awake and keeping the body to sleep to see and hear stuff that never happend, then get to a lucid dream.
[QUOTE=that dumshit writer of the article;36731334]gotten kicked by a bed partner,[/QUOTE] What? This happens?
It's really cool to induce sleep paralysis.
[QUOTE=Naaz;36731497]What? This happens?[/QUOTE] I apparently punched my sister in this face while I was sleeping when we had to share a bed at our grandparents house.
[QUOTE=Edthefirst;36731572]It's really cool to induce sleep paralysis.[/QUOTE] holy shit no it isn't. it's fucking terrifying
[QUOTE=Edthefirst;36731572]It's really cool to induce sleep paralysis.[/QUOTE] having suffered sleep paralysis in the past, i can safely say [I]it fucking isn't.[/I]
[QUOTE=Dr.C;36731601]I apparently punched my sister in this face while I was sleeping when we had to share a bed at our grandparents house.[/QUOTE] Done the same thing. Well, I claimed I was sleeping, anyway. No one bought that story though, possibly because we were in the living room watching TV
[QUOTE=Dr.C;36731601]I apparently punched my sister in this face while I was sleeping when we had to share a bed at our grandparents house.[/QUOTE] Same. However it wasn't my fist.
SLeep paralysis is the scariest fucking thing.
A week ago it was like 7am and apparently something in my dream made me kick like fucking a donkey which proceeded with me kicking everything off my night stand :v:
Sleep Paralysis happened to me this morning after I turned off my alarm and went back to sleep. It always freaks me out, and I try so hard to open my eyes and control my breathing. Sleep paralysis has always been one of the most horrible things that I believe everybody should experience at least once.
[QUOTE=Xion12;36731723]Sleep Paralysis happened to me this morning after I turned off my alarm and went back to sleep. It always freaks me out, and I try so hard to open my eyes and control my breathing. Sleep paralysis has always been one of the most horrible things that I believe everybody should experience at least once.[/QUOTE] It is such a bizarre feeling. My eyes were wide open when it happened and I was scared shitless as I tried to will my body to move but nothing would respond. My whole body felt...disconnected, for lack of a better word. Lasted almost 20 minutes.
I used to kick the sheets off, like right off the bed, I'd wake up in the morning and they'd be across the room. I grew out of it though, thank god.
I've always tried to induce lucid dreaming by laying down completely still while keeping my mind active so I don't fall asleep. It feels really weird, but I usually end up stopping because of the stories I've heard.
I don't remember suffering from sleep paralysis... I'm busy trying to learn to control my dreams when I'm sleeping.
One of my friends suffers from the lack of sleep paralysis. For whatever reason, he still moves around in his sleep. Usually, it's just kicking the blankets off of himself but sometimes he gets up and wanders around, possibly hurting himself. One time, he woke up and his hands and arms were cut quite badly and he didn't know how it happened.
[QUOTE=Xion12;36731723]Sleep Paralysis happened to me this morning after I turned off my alarm and went back to sleep. It always freaks me out, and I try so hard to open my eyes and control my breathing. Sleep paralysis has always been one of the most horrible things that I believe everybody should experience at least once.[/QUOTE] I have had sleep paralysis multiple times a morning for about 8 years now. I hope they eventually find a way to stop it because doctors don't have a clue.. I'm used to it and can avoid the panic but it still disturbs me from how unbelievably vivid the hallucinations are.
If you have sleep paralysis, try to relax because everything you see can't hurt you and isn't real. I've been practicing lucid dreaming and I use sleep paralysis (WILD Method) to induce it.
Sleep paralysis happens to me quite often and I always feel that I'm actually inducing it. The other annoying aspect apart from it being scary is that fact that once I get out of it and go back to sleep, I do it again moments later and repeat it numerous times. Gets very irritating.
I don't know any of this nonsense you guys are talking about, I just lay back and wait until my eyes open again in the morning.
Inducing sleep paralysis to a person in a sound room to me is hard to fathom for me in how dreadful it would be.
[QUOTE=Ninja Duck;36732467]I don't know any of this nonsense you guys are talking about, I just lay back and wait until my eyes open again in the morning.[/QUOTE] Aye. Never had this horrible experience you folks describe. Guess I'm lucky.
I do not really have issues with this, but I usually end up either completely uncovered or in a different position, but that's about it every now and then I wake up with no clothes on (I sleep with only undershorts on)
The only dangerous thing I do in my sleep is roll over and kick the wall. Never hard enough to dent it, but it makes a really loud noise.
I've always wanted to experience sleep paralysis just to see what it's like.
[QUOTE=vexx21322;36732623]I've always wanted to experience sleep paralysis just to see what it's like.[/QUOTE]http://www.world-of-lucid-dreaming.com/wake-induced-lucid-dreams.html You can induce it.
It's really fun sometimes you just chill there being unable to move, then close your eyes and picture what you want. Some say the trick to snap out is to hold your breath,
Sorry, you need to Log In to post a reply to this thread.