A bit of boron, a pinch of palladium: One-stop shop for an infinite variety of organic molecules - Polidicks

[release] [B]Carbon-containing compounds are at the heart of organic chemistry, and carbon is the basis of all living matter. However, the so-called Suzuki reaction provides a simple means of creating carbon-carbon bonds to form compounds that can serve as the starting points for the synthesis of an infinite variety of organic molecules. [/B] A team of researchers led by chemist Professor Paul Knochel from Ludwig-Maximilians-Universitaet (LMU) in Munich has recently developed a practical and general method for the synthesis of a class of intermediates that readily undergo the Suzuki reaction. "The new method is broadly applicable to diverse starting compounds and is very economical because it produces very few unwanted byproducts," says Knochel. "It should also be of great interest in an industrial setting, where Suzuki reactions are used in the development of medicinal compounds and novel materials such as liquid crystals for display screens." The Suzuki reaction – [highlight]which involves the use of palladium to catalyze the cross-coupling of organoboron compounds with organic halogen-containing molecules – makes it possible to link carbon atoms together in a very straightforward way.[/highlight] The products of the reaction can then be utilized for the construction of a [highlight]virtually unlimited number of organic substances[/highlight]. [highlight]The Suzuki reaction thus forms the basis for the synthesis of novel drugs and innovative materials[/highlight]. Akira Suzuki was awarded the Nobel Prize in Chemistry for his discovery of the reaction that bears his name. Knochel and his team were hoping to extend the applicability of the reaction by finding an easy, economical and general way to synthesize the necessary organoboron compounds so that they could be used in Suzuki reactions without further purification. "We were able to optimize the process in such a way that the boronates can be made in a one-pot reaction", says Christoph Sämann, who made a major contribution to the study. "The method works well under very mild conditions, is compatible with many different functional groups and can therefore be applied to a wide range of compounds." In contrast to the organoboronates that have been used so far, [highlight]the products generated via the new synthetic route have two organic groups attached to the boron atom, and both can be transferred, without loss, in the course of the subsequent Suzuki reaction.[/highlight] "This significantly improves overall yields, making the reaction much more economical," says Knochel. "The new reaction also produces less waste, which is an especially important consideration in industrial applications." (suwe)[/release] [URL="http://www.physorg.com/news/2011-08-bit-boron-palladium-one-stop-suzuki.html"]Source[/URL] [url="http://onlinelibrary.wiley.com/doi/10.1002/anie.201104437/abstract"]Abstract[/url]

And yet billions of people abolish the notion of evolutionism, and the natural, chemical creation of life. Science is awesome.

[QUOTE=SweetSwifter;31485512]And yet billions of people abolish the notion of evolutionism, and the natural, chemical creation of life. Science is awesome.[/QUOTE] evolutionism is not a word the terms are evolution and abiogenesis Damn it people, learn you're word's wright.

[QUOTE=SweetSwifter;31485512]And yet billions of people abolish the notion of evolutionism, and the natural, chemical creation of life. Science is awesome.[/QUOTE]Anyone I know who think evolution is wrong doesn't understand it, if it makes you feel any better.

[QUOTE=Mr. Scorpio;31485534]evolutionism is not a word the terms are evolution and abiogenesis Damn it people, learn you're word's wright.[/QUOTE] Yeah I wish people learned they're words right god damnit

[QUOTE=SweetSwifter;31485512]And yet billions of people abolish the notion of evolutionism, and the natural, chemical creation of life. Science is awesome.[/QUOTE]I know i am.

[QUOTE=Nerts;31485549]Anyone I know who think evolution is wrong doesn't understand it, if it makes you feel any better.[/QUOTE] My best friend is Christian and his entire family disavows evolution because "we're just too perfectly made to be an accident". No matter what I say they can't get over that. *headdesk*

[QUOTE=RetaDepa;31485558]Yeah I wish people learned they're words right god damnit[/QUOTE] I gnow. People are so dubius. [editline]2nd August 2011[/editline] [QUOTE=deathstarboot;31485575]My best friend is Christian and his entire family disavows evolution because "we're just too perfectly made to be an accident". No matter what I say they can't get over that. *headdesk*[/QUOTE] except, you know all the flaws in the human body

This sounds very useful indeed. May be handy for synthesizing new materials. Also, offtopic, I request the source of RetaDepa's avatar.

Fantastic, Suzuki reactions are already awesome. [editline]2nd August 2011[/editline] For those who have no idea about the suzuki reaction, simply, it allows scientists to synthesize more chemicals. For example, some otherwise prohibitively expensive and otherwise unavailable (possible) cancer drugs can now be created in the law relatively cheaply, and investigated as a cure. In addition, the reactants are relatively non-toxic, and the reaction only decreases the catalyst by a small amount each time.

Indeed, it almost sounds like organic alchemy.

[QUOTE=deathstarboot;31485575]My best friend is Christian and his entire family disavows evolution because "we're just too perfectly made to be an accident". No matter what I say they can't get over that. *headdesk*[/QUOTE]Exactly what I mean. Although nothing annoyed me more than this one guy in a biochemistry class I had a couple of years ago who took absolutely everything else in the class as a fact, except for evolution, arguing that it was wrong because the bible said something different, even though he conceded that all the evidence for it and methods involved were accurate a correct. I don't mind other people 's personal beliefs, but this guy was a stubborn idiot who wouldn't be quiet.

[QUOTE=deathstarboot;31485575]..."we're just too perfectly made to be an accident"...[/QUOTE] Humanity is perfect? Oh wow, talk about being massively delusional.

According to our definition of perfect, we are not perfect.

[QUOTE=deathstarboot;31485575]My best friend is Christian and his entire family disavows evolution because "we're just too perfectly made to be an accident". No matter what I say they can't get over that. *headdesk*[/QUOTE] Really? That's their "defense" as in, humans are too perfect to be a natural "accident" ? I mean, it amazes me too actually how right conditions and shit can create such a fucking world we live in. It's a miracle.. Anyway I wouldn't call it an accident necessarily, it just shows the result of billions of years of development, all basically starting from the big bang.. And some natural force which we might as well call luck.

the world seems perfectly suited to us because we adapted to it over a long period of time

[QUOTE=TheHydra;31487902]the world seems perfectly suited to us because we adapted to it over a long period of time[/QUOTE] not to mention that, you know it isn't ever tried living life without clothes or tools? Or in a cold environment? Or in a hot environment? Or in the ocean? this planet actually kind of sucks to live on

[QUOTE=paul simon;31486947]According to our definition of perfect, we are not perfect.[/QUOTE] I am.

[QUOTE=Mr. Scorpio;31487984]not to mention that, you know it isn't ever tried living life without clothes or tools? Or in a cold environment? Or in a hot environment? Or in the ocean? this planet actually kind of sucks to live on[/QUOTE] Uhh what. There are animals living in very cold environments, also in very hot environments, and in the depths of the ocean. and humans can go to p. much all of those places with the use of technology. that comes from our planet.

[QUOTE=Gekkosan;31488044]Uhh what. There are animals living in very cold environments, also in very hot environments, and in the depths of the ocean. and humans can go to p. much all of those places with the use of technology. that comes from our planet.[/QUOTE]He means humans without technology.

[QUOTE=Mr. Scorpio;31487984]not to mention that, you know it isn't ever tried living life without clothes or tools? Or in a cold environment? Or in a hot environment? Or in the ocean? this planet actually kind of sucks to live on[/QUOTE] Instead of humans developing physical adaptations to better cope with the environment (ie thicker fur, stronger muscles, etc) we developed attributes that helped us function better as a society, including an improved tongue that allows for formation of more complex vocal sounds, and an increased cranial cavity due to our skulls not having to harbour a huge jaw muscle like many apes do. In short, we didn't get harder better faster stronger, we learned the magic of friendship and worked together to solve shit.

[QUOTE=Nerts]humans without technology[/QUOTE] That's just unnatural. Human infants have enough curiosity to pick up a stick and whack shit with it, and surely an isolated adult would be bored out of their mind looking for stuff to do; human adaptation implies human technology.

Palladium in the chest is a painful way to die.

Why can't people be open to the fact that evolution is a real thing. They could even incorporate it into their religions.. Maybe God (or whomever they celebrate as the highest of high) coulda laid the groundwork for life and let everything play out.

[QUOTE=deathstarboot;31485575]"we're just too perfectly made to be an accident"[/QUOTE] People actually say and stand by that?

[QUOTE=Mechwarrior;31493734]Why can't people be open to the fact that evolution is a real thing. They could even incorporate it into their religions.. Maybe God (or whomever they celebrate as the highest of high) coulda laid the groundwork for life and let everything play out.[/QUOTE] Well thats what rational theists believe but there aren't many of those.

[QUOTE=Night-Eagle;31490626]That's just unnatural. Human infants have enough curiosity to pick up a stick and whack shit with it, and surely an isolated adult would be bored out of their mind looking for stuff to do; human adaptation implies human technology.[/QUOTE] By that definition, ravens, monkeys and so on have an array of technology. [editline]3rd August 2011[/editline] [QUOTE=Mikedestruct;31495528]Well thats what rational theists believe but there aren't many of those.[/QUOTE] Not in your country, but it seems to be the accepted version of events for most catholics I know. [editline]3rd August 2011[/editline] [QUOTE=Azur;31488170]we learned the magic of friendship and worked together to solve shit.[/QUOTE] I think you've been watching too much: [img]http://www.watchcartoononline.com/thumbs/My-Little-Pony-Friendship-is-Magic-Episode-21-Over-a-Barrel.jpg[/img]

[B]For those that don't know what this newspost means[/B], it's basically that boron, and especially palladium, can catalyze the formation of carbon-carbon bonds which is pretty damn hard to go otherwise. Organic chemistry is really fascinating. For example, recently they discovered a molecule called "bis(bis(N-trimethylsilyliminodiphenylphosphorano methanide uranium iodo) toluenediide" which looks like [img]http://www.nature.com/nchem/journal/v3/n6/thumbs/nchem.1028-comp5.gif[/img] which could replace the Neodyminium-Boron-Iron magnets since it's magnetic itself, and could be used to replace those Nd magnets in say HDDs. It astonishes me that there's people who believe in Science yet they also believe in a God. Sorry but how can you believe there's protons and electrons, believe in the fantastic formula E=mc^2 and yet believe in a God?

[QUOTE=Mechwarrior;31493734]Why can't people be open to the fact that evolution is areal thing.[/QUOTE] Evolution is a theory. It hasn't been proven and there could possibly be another solotion. That being said, evolution is the most plausible and accepted theory out there, and i personally think that that is why we exist.

[QUOTE=deathstarboot;31485575]My best friend is Christian and his entire family disavows evolution because "we're just too perfectly made to be an accident". No matter what I say they can't get over that. *headdesk*[/QUOTE] Do you actually get into religious arguments with your best friend's family because that's not good table manners