• Stem Cell Dental Implants grow New Teeth Right in your Mouth
    74 replies, posted
[quote]NEW YORK (May 19, 2010) - A technique pioneered in the Tissue Engineering and Regenerative Medicine Laboratory of Dr. Jeremy Mao, the Edward V. Zegarelli Professor of Dental Medicine at Columbia University Medical Center, can orchestrate stem cells to migrate to a three-dimensional scaffold infused with growth factor, holding the translational potential to yield an anatomically correct tooth in as soon as nine weeks once implanted. People who have lost some or all of their adult teeth typically look to dentures, or, more recently, dental implants to improve a toothless appearance that can have a host of unsettling psycho-social ramifications. Despite being the preferred (but generally painful and potentially protracted) treatment for missing teeth nowadays, dental implants can fail and are unable to “remodel” with surrounding jaw bone that undergoes necessary changes throughout a person’s life. An animal-model study has shown that by homing stem cells to a scaffold made of natural materials and integrated in surrounding tissue, there is no need to use harvested stem cell lines, or create an environment outside of the body (e.g., a Petri dish) where the tooth is grown and then implanted once it has matured. The tooth instead can be grown “orthotopically,” or in the socket where the tooth will integrate with surrounding tissue in ways that are impossible with hard metals or other materials. "These findings represent the first report of regeneration of anatomically shaped tooth-like structures in vivo, and by cell homing without cell delivery,” Dr. Mao and his colleagues say in the paper. "The potency of cell homing is substantiated not only by cell recruitment into scaffold microchannels, but also by the regeneration of periodontal ligaments and newly formed alveolar bone." This study is published in the most recent Journal of Dental Research, the top-rated, peer-reviewed scientific journal dedicated to the dissemination of new knowledge and information on all sciences relevant to dentistry, the oral cavity and associated structures in health and disease. Dental implants usually consist of a cone-shaped titanium screw with a roughened or smooth surface and are placed in the jaw bone. While implant surgery may be performed as an outpatient procedure, healing times vary widely and successful implantation is a result of multiple visits to different clinicians, including general dentists, oral surgeons, prosthodontists and periodontists. Implant patients must allow two to six months for healing and if the implant is installed too soon, it is possible that the implant may fail. The subsequent time to heal, graft and eventually put into place a new implant may take up to 18 months. The work of Dr. Mao and his laboratory, however, holds manifold promise: a more natural process, faster recovery times and a harnessing of the body’s own potential to re-grow tissue that will not give out and could ultimately last the patient’s lifetime. “A key consideration in tooth regeneration is finding a cost-effective approach that can translate into therapies for patients who cannot afford or who aren’t good candidates for dental implants,” Dr. Mao says. “Cell-homing-based tooth regeneration may provide a tangible pathway toward clinical translation.” Dr. Ira B. Lamster, dean of the College of Dental Medicine, stated: “This research provides an example of what is achievable when today’s biology is applied to common clinical problems. Dr. Mao’s research is a look into the future of dental medicine.” This research was supported by NIH ARRA Funding via 5RC2 DE020767 from the National Institute of Dental and Craniofacial Research. Columbia has filed patent applications relating to the engineered tooth and, through its technology transfer office, Columbia Technology Ventures, is actively seeking partners to help commercialize the technology.[/quote] Pretty spectacular, no? Stem Cell research really needs more funding. [url=http://cumc.columbia.edu/news/press_releases/MAOtooth.html]Source[/url]
But it's against gods will! :downs:
Screw God, give me teeth.
[QUOTE=radioactive;22214815]But it's against gods will! :downs:[/QUOTE] No it is not. It's against will of people who bend and misunderstand the whole thing.
[QUOTE=Awesomecaek;22214835]No it is not. It's against will of people who bend and misunderstand bible.[/QUOTE] AKA the clergy who wants your money. As they've done since the beginning of time.
That's pretty cool. Now give me three arms.
[QUOTE=SuPeR_MaN;22214879]That's pretty cool. Now give me three arms.[/QUOTE] I know what you're thinking and no. That's two sins in one you monster.
Fuck yeah. Now I don't have to worry about my teeth being fucked up from the horridly lack of fluoride in Arizona's water.
This will be useful when all my teeth are fucked up beyond all repair in 10 years.
I really hate those religious fucks who are always in the way of Stem Cell research. I really wish it does get more funding.
[QUOTE=SuPeR_MaN;22214879]That's pretty cool. Now give me three arms.[/QUOTE] you could jack off THREE guys at the SAME TIME
[QUOTE=KmScMT;22215189]you could jack off THREE guys at the SAME TIME[/QUOTE] You could wash your teeth and dry your hair all while masturbating at the same time.
[QUOTE=wewt!;22215211]You could wash your teeth and dry your hair all while masturbating at the same time.[/QUOTE] You could browse for porn (mouse in hand), drink Red Bull and fap at the same time!
Until it goes wrong and grows teeth cancer!
[QUOTE=sloppy_joes;22214845]AKA the clergy who wants your money. As they've done since the beginning of time.[/QUOTE] Not all of them. Not even most of them. Sadly, those who did and do are the most remembered ones.
Well, if this goes commercial, someone's gonna make a fortune from selling the implants to old people what wear dentures...
Fuckin' stem cells, how do they work? No seriously, these things are way more like magic than magnets are. Why didn't ICP sing about them?
cause they have no clue what they are.
That's pretty incredible that we have the technology to do this nowadays, just imagine what we'll have 10 years from now.
I could use this.... :raise:
Holy fucking shit isn't science the most awesome thing?=
[QUOTE=JoeSkylynx;22214961]Fuck yeah. Now I don't have to worry about my teeth being fucked up from the horridly lack of fluoride in Arizona's water.[/QUOTE] Because sodium fluoride is good for your teeth :downs:
[QUOTE=Awesomecaek;22214835]No it is not. It's against will of people who bend and misunderstand the whole thing.[/QUOTE] You are wrong, it is obviously and clearly against the will and god, and it is a sin to use Stem Cells. :downs: Also, Obama is a Communist and Glenn Beck is a great man and Terrorists and 9/11. :downs: Also 2010 Vote Palin :downs:
[QUOTE=radioactive;22218670]You are wrong, it is obviously and clearly against the will and god, and it is a sin to use Stem Cells. :downs: Also, Obama is a Communist and Glenn Beck is a great man and Terrorists and 9/11. :downs:[/QUOTE] You forgot: "2010 Vote Palin :downs: "
okay science, now please get a stargate working [editline]10:54PM[/editline] then i have EVERYTHING
[QUOTE=raviool;22218947]okay science, now please get a stargate working [editline]10:54PM[/editline] then i have EVERYTHING[/QUOTE] You don't have Spicy Space Beefs.
I wonder how much that would cost. Problems with your teeth are already expensive as hell.
[QUOTE=Johnnsen;22218980]I wonder how much that would cost. Problems with your teeth are already expensive as hell.[/QUOTE] It would make current operations cheaper.
[QUOTE=radioactive;22218996]It would make current operations cheaper.[/QUOTE] The question is if they will really charge less for it. Or if there will be some reason why it will be more expensive. Anyway, the thought of it is great, would make a lot of things easier.
I wonder if you could make them heal wounds in a battlefield..
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