• US First: Cold Virus Used To Treat Brain Cancer At UAMS
    4 replies, posted
[quote]LITTLE ROCK, Ark. (November 16, 2016) — In the first time the method has been used in the United States, doctors injected a cold virus into a Hazen woman’s brain tumor in an effort to eradicate it as part of a clinical trial at the University of Arkansas for Medical Sciences (UAMS). J.D. Day, M.D., professor and chairman of the Department of Neurosurgery in the UAMS College of Medicine, performed the surgery and described the treatment as a combination of therapies that he hopes will destroy Rogers’ cancer. If successful, he hopes the treatment will become a first line of defense for patients and doctors in treating glioblastomas. During the surgery, Day used a new and specially designed cannula to inject Rogers’ tumor with an adenovirus, which is a common cause of respiratory illness. Once in place, the virus began multiplying, attacking cancer cells but not affecting healthy cells. The virus replicates on its own, continuing the attack as long as cancer cells are present, so no further injections will be needed. A few additional U.S. sites were approved to take part in the phase two trial, called CAPTIVE – Combination Adenovirus + Pembrolizumab to Trigger Immune Virus Effects – but when Rogers was identified as an ideal participant, UAMS became the first to actually perform the procedure.[/quote] [url=http://www.thv11.com/news/local/first-time-in-us-virus-used-to-attack-brain-tumor-at-uams/352747902]Source[/url] Hopefully it ends up working out for her!
This. This is the future I want. Is there any way this can work for other cancers, like Pancreatic? My relatives are working on an immune response triggering to skin cancer, but ofc that doesn't really apply to many other types
[QUOTE=chipsnapper2;51383212]This. This is the future I want. Is there any way this can work for other cancers, like Pancreatic? My relatives are working on an immune response triggering to skin cancer, but ofc that doesn't really apply to many other types[/QUOTE] [quote]The combination of treatments has proven successful with other types of cancer, but this is the first time it has been tried with a brain tumor.[/quote] Just a local news site, so not much more info than that
How does one engineer a virus to only affect cells with specific cancerous mutations?
[QUOTE=bitches;51383245]How does one engineer a virus to only affect cells with specific cancerous mutations?[/QUOTE] [url=https://en.wikipedia.org/wiki/Oncolytic_virus#Engineering_oncolytic_viruses]From Wikipedia[/url]
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