Translating Cancer Research into Treatment; An Outlook

[Kagrenak]

Wall of imaged text below, [b]shorter summary at bottom if you're lazy[/b];

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Sorry about the images, there's no good way to format it from the text version of the article. This is an interesting article about translational research in cancer therapeutics and the difficulties associated with drug development and rollout, so I figured it was worth it.

Some interesting things mentioned are the change from traditional randomized trials to the development of biomarker based trials that target specific populations and subsets of cancers, decreasing overall cytotoxicity and increasing specificity of treatments. They propose that this shift would alleviate a common bottleneck in cancer treatment rollout, while still allowing for the treatments to be evidence based and sucessful in larger cohorts of patients. The authors highlight selected clinical trials both in the new/proposed framework to illustrate their perspective. Interestingly, the current average cost of developing a treatment under the current schema is: [b]One Billion USD[/b]. Hopefully the new forms of development and clinical trial procedures outlined within this article may be able to reduce the price, while increasing the efficacy and safety of future treatments.

[clockroach]

no one is going to read this

[Kagrenak]

[QUOTE=clockroach;25282151]no one is going to read this[/QUOTE]

I have a short summary. (it's hard to summarize a 6 pg document on such a complex topic into something that a bunch of ADHD FPers will want to read.)