DEA approves Ecstasy for clinical trials. - Polidicks

[QUOTE] The U.S. Drug Enforcement Administration (DEA) has approved the first clinical trial using MDMA along with psychotherapy to treat anxiety among people with life-threatening illnesses, researchers told Al Jazeera on Tuesday, adding that public support for the therapeutic use of psychedelic drugs is rapidly growing. "The tide has changed for psychedelic research," said Brad Burge, the communications director for the Multidisciplinary Association for Psychedelic Studies (MAPS), a California-based nonprofit research group that studies medicinal uses for psychedelics and marijuana and is sponsoring the study. The DEA approved the project on Friday, he said. Unlike Ecstasy or Molly — names for MDMA sold on the street and often mixed with dangerous adulterants — pure MDMA has been proved “sufficiently safe” when taken a limited number of times in moderate doses, MAPS says on its website. The DEA did not immediately respond to a request for comment. MDMA can be useful in psychotherapy for people suffering from anxiety due to life-threatening illnesses because it produces in users a sense of calm, trust and confidence, Burge said. Unlike psychedelics such as LSD and psilocybin, MDMA does not produce hallucinations, he added. The clinical trial will be held in Marin, California, in a psychologist’s office, as opposed to a hospital setting, Burge said. The patients will lie on a couch with a therapist nearby for support and conversation. In the trial, 18 subjects diagnosed with life-threatening illnesses will attend months of psychotherapy, with MDMA being used in a few sessions in order to facilitate the process, he said. The outcome will be measured by whether using the psychedelic helps reduce people's anxiety, which will be determined at the end of the sessions by the patient’s feedback and the therapist's assessments. Researchers hope that using MDMA alongside psychotherapy will let subjects confront their situation more clearly and allow the positive steps they take during the therapy to "stick," Burge said. "It opens them up and makes them more comfortable with the therapist while reducing fear and making them more able to talk about difficult emotions." If the pilot is successful, MAPS plans to continue with further studies involving more subjects and different approaches. For now, researchers hope to establish basic safety and effectiveness, he said. [/QUOTE] [url]http://america.aljazeera.com/articles/2015/3/17/clinical-trial-approved-for-mdma-psychotherapy.html[/url]

Progress!

You spelled ecstasy wrong.

-snoop-

Count me in! Let me "test" some with some friends!

[quote] MDMA does not produce hallucinations[/quote] I've hallucinated a bunch of times on MDMA, usually after taking ~ 0.3points of a gram, what is this what

[QUOTE=mr apple;47668766]I've hallucinated a bunch of times on MDMA, usually after taking ~ 0.3points of a gram, what is this what[/QUOTE] Perhaps this is in the traditional understanding of hallucinogens where you see things that aren't there? As opposed to visual alterations

Oh shit so does this mean you might be able to get a prescription for MDMA somewhere down the line? Kickass. Although from the way it sounds in the article, the problems you'd need to have to GET the prescription would likely get your ass brady acted.

There's analogues to MDMA which would be much better for clinical use. MDMA's insanely neurotoxic - experienced recreational users say to only do it maybe once every 2-3 months, 1 month if you feel like pushing it. There's synthetic, albeit very untested drugs, that are less neurotoxic and show way more promise than MDMA. It's good that the government is starting to allow more medical testing of schedule 1 drugs, but I wish they'd be more open to medical testing of modern synthetic alphabet-soup drugs. A cocktail of 2-FMA, 5-MAPB, and 4-HO-MET (or 5-MeO-MiPT) can make an identical empathogenic reaction as MDMA without the neurotoxicity and the really really rough comedown of MDMA.

[QUOTE=.Isak.;47668924]There's analogues to MDMA which would be much better for clinical use. MDMA's insanely neurotoxic - experienced recreational users say to only do it maybe once every 2-3 months, 1 month if you feel like pushing it. There's synthetic, albeit very untested drugs, that are less neurotoxic and show way more promise than MDMA. It's good that the government is starting to allow more medical testing of schedule 1 drugs, but I wish they'd be more open to medical testing of modern synthetic alphabet-soup drugs. A cocktail of 2-FMA, 5-MAPB, and 4-HO-MET (or 5-MeO-MiPT) can make an identical empathogenic reaction as MDMA without the neurotoxicity and the really really rough comedown of MDMA.[/QUOTE] The thing is that clinical therapy with MDMA has been found to not require continuous treatment like other anti-depressants and anti-anxiety medications. It's a regimen administered a few times over the period of the weeks or months of therapy, with the intended net result being a stable and enduring improvement in the sense of self, security, and agency.

[QUOTE=mr apple;47668766]I've hallucinated a bunch of times on MDMA, usually after taking ~ 0.3points of a gram, what is this what[/QUOTE] Recreational drugs are prone to the placebo effect, where the effects are exaggerated or even imagined into existence because one expects it. That could have been the cause

[QUOTE=Karmah;47668988]Recreational drugs are prone to the placebo effect, where the effects are exaggerated or even imagined into existence because one expects it. That could have been the cause[/QUOTE] That's one hell of a placebo

[QUOTE=.Isak.;47668924]There's analogues to MDMA which would be much better for clinical use. MDMA's insanely neurotoxic - experienced recreational users say to only do it maybe once every 2-3 months, 1 month if you feel like pushing it. There's synthetic, albeit very untested drugs, that are less neurotoxic and show way more promise than MDMA. It's good that the government is starting to allow more medical testing of schedule 1 drugs, but I wish they'd be more open to medical testing of modern synthetic alphabet-soup drugs. A cocktail of 2-FMA, 5-MAPB, and 4-HO-MET (or 5-MeO-MiPT) can make an identical empathogenic reaction as MDMA without the neurotoxicity and the really really rough comedown of MDMA.[/QUOTE] I don't know what the fuck you're talking about, but baby steps lol. Let's start out with MDMA and LSD and shit and work our way up to that you know. Are you trying to give the US government a heartattack? Take it easy dirty harry and like I said, let's start with they we know. (not that I know what any of that shit is but hey baby steps right?) [editline]6th May 2015[/editline] [QUOTE=Karmah;47668988]Recreational drugs are prone to the placebo effect, where the effects are exaggerated or even imagined into existence because one expects it. That could have been the cause[/QUOTE] To a very, VERY lenient extent.. :v: In support of your statement weed, tramadol and adderall and the like though can be but not much else. Unless you get some shoddy molly, but again that will only ever live up to your expectations of what a substance really is capable of.

[QUOTE=.Isak.;47668924]There's analogues to MDMA which would be much better for clinical use. MDMA's insanely neurotoxic - experienced recreational users say to only do it maybe once every 2-3 months, 1 month if you feel like pushing it. There's synthetic, albeit very untested drugs, that are less neurotoxic and show way more promise than MDMA. It's good that the government is starting to allow more medical testing of schedule 1 drugs, but I wish they'd be more open to medical testing of modern synthetic alphabet-soup drugs. A cocktail of 2-FMA, 5-MAPB, and 4-HO-MET (or 5-MeO-MiPT) can make an identical empathogenic reaction as MDMA without the neurotoxicity and the really really rough comedown of MDMA.[/QUOTE] Actually iirc the neurotoxicity of MDMA is proportional to the temperature of the user when taken at recreational doses

Suddenly chewing gum sales in hospitals sky-rocket.

[QUOTE=Karmah;47668988]Recreational drugs are prone to the placebo effect, where the effects are exaggerated or even imagined into existence because one expects it. That could have been the cause[/QUOTE] lol [QUOTE=Lick;47668786]Perhaps this is in the traditional understanding of hallucinogens where you see things that aren't there? As opposed to visual alterations[/QUOTE] Wasn't really just visual alterations, I definitely know when I'm hallucinating, tis usually stronger at night than during the day, mostly because of shadows maybe. The first time it happened freaked me the fuck out because I didn't know you could hallucinate on MDMA at all, started off by seeing a huge spiderweb that went across the roof of my balcony, but whenever I shined a torch around it, the spider web would still be 'around' the torch light. Whenever I looked at my friends face, I'd every now and then see someone elses face as his, kept seeing people down the road walking towards me. Had to literally sit there for a minute and try and focus on what the actual object was and tell myself that it wasn't real. Once I found out I was hallucinating, it's pretty cool, you can somewhat control them a tiny bit. Depends on how munted you are

[IMG]http://www.sickchirpse.com/wp-content/uploads/2015/03/Weed.jpg[/IMG] Weed is schedule 1, mdma is schedule 1, where are the weed trials? Am I the only one thinking this?

[QUOTE=mr apple;47669856]Whenever I looked at my friends face, I'd every now and then see someone elses face as his, kept seeing people down the road walking towards me. Had to literally sit there for a minute and try and focus on what the actual object was and tell myself that it wasn't real.[/QUOTE] This type of shit I would get very often when taking ecstasy, but full blown hallucinations requires a larger dose. Smoking weed along with it makes me hallucinate even more. If I remember correctly, the hallucinations happen because at higher doses the mdma turns into mda or something, also some ecstasy contain mda.

I just wonder how mild these prescriptions would be because in my experience, MDMA only did shit for me when I snorted it and then I'd just be on the ground sort of scream/exhaling very loudly but like in a really nice and soothing sort of way that I just can't imagine being the norm for these trials.

yo homes, is dope worth tryin? [editline]6th May 2015[/editline] tryin to bust some chill man, just sayin

gg club drugs division [img]http://thumbs1.ebaystatic.com/d/l225/m/mgMWC3RSzFlnNp72z5iwHeg.jpg[/img] this patch makes it look like a blast it's like they're actually advocating usage of ecstacy

[QUOTE=old_hag12;47670448] Weed is schedule 1, mdma is schedule 1, where are the weed trials? Am I the only one thinking this?[/QUOTE] [url]http://medicalmarijuana.procon.org/view.resource.php?resourceID=000881[/url]

[QUOTE=old_hag12;47670448][IMG]http://www.sickchirpse.com/wp-content/uploads/2015/03/Weed.jpg[/IMG] Weed is schedule 1, mdma is schedule 1, where are the weed trials? Am I the only one thinking this?[/QUOTE] Wrong thread. There already is medicinal cannabis anyway. [editline]6th May 2015[/editline] [QUOTE=.Isak.;47668924]There's analogues to MDMA which would be much better for clinical use. MDMA's insanely neurotoxic - experienced recreational users say to only do it maybe once every 2-3 months, 1 month if you feel like pushing it. There's synthetic, albeit very untested drugs, that are less neurotoxic and show way more promise than MDMA. It's good that the government is starting to allow more medical testing of schedule 1 drugs, but I wish they'd be more open to medical testing of modern synthetic alphabet-soup drugs. A cocktail of 2-FMA, 5-MAPB, and 4-HO-MET (or 5-MeO-MiPT) can make an identical empathogenic reaction as MDMA without the neurotoxicity and the really really rough comedown of MDMA.[/QUOTE] If you take 100mg one off you'll be fine, it only has lasting neurotoxic effects if you're a long term user or taking a large amount in a short period of time.

[QUOTE=mr apple;47668766]I've hallucinated a bunch of times on MDMA, usually after taking ~ 0.3points of a gram, what is this what[/QUOTE] typically the kind of mdma you'll buy anywhere has other stuff added to it for user enjoyment, less you've verified the chemical integrity of what you've purchased.

[QUOTE=Mobon1;47670929]typically the kind of mdma you'll buy anywhere has other stuff added to it for user enjoyment, less you've verified the chemical integrity of what you've purchased.[/QUOTE] Always test it, you could get [URL="http://en.wikipedia.org/wiki/Para-Methoxy-N-methylamphetamine"]PMMA[/URL] or [URL="http://en.wikipedia.org/wiki/Para-Methoxyamphetamine"]PMA[/URL] instead which will kill you with 1/4 the dose MDMA would.

[QUOTE=Karmah;47668988]Recreational drugs are prone to the placebo effect, where the effects are exaggerated or even imagined into existence because one expects it. That could have been the cause[/QUOTE] One night in a club I tripped so hard I thought the room was a train carriage, then I kept seeing the Battlefield 3 deploy screen and kept trying to "click" on the spawn points... Then a bunch of us were queueing for the first underground train home and I thought this electrical cupboard was a fucking cart of hay with some guys sat on it that were calling my name. I yelled back "YEAH?!" then snapped out of it and everyone was staring at me... I can honestly say I was not expecting that didnt even know you could trip on MDMA

[QUOTE=mr apple;47669856]lol Wasn't really just visual alterations, I definitely know when I'm hallucinating, tis usually stronger at night than during the day, mostly because of shadows maybe. The first time it happened freaked me the fuck out because I didn't know you could hallucinate on MDMA at all, started off by seeing a huge spiderweb that went across the roof of my balcony, but whenever I shined a torch around it, the spider web would still be 'around' the torch light. Whenever I looked at my friends face, I'd every now and then see someone elses face as his, kept seeing people down the road walking towards me. Had to literally sit there for a minute and try and focus on what the actual object was and tell myself that it wasn't real. Once I found out I was hallucinating, it's pretty cool, you can somewhat control them a tiny bit. Depends on how munted you are[/QUOTE] The visual distortions are necessarily a part of the effects of MDMA. While MDMA can cause lights to be brighter and affect your vision to an extent, it does not produce the hallucinations. High doses of MDMA does tend to cause significant nystagmus(where your eyes wiggle back and forth uncontrollably). However, a certain percentage of MDMA is metabolized into MDA in your liver; I believe its like 15% or so(too lazy to look it up). Not only that, but since MDA is a precursor to MDMA synthesis, what you're taking might not always be pure MDMA. This is why you can experience visualizations during your roll, and moreso on the comedown. I remember reading a reddit thread where the OP laid out a very legit sounding reason as to why MDMA is neurotoxic. It's because the metabolization of MDA leads to neurotoxic byproducts. IF his theory is correct, then by inhibiting the enzymes that break MDMA into MDA, neurotoxicity could be made null. Obviously there's other risks to taking such a powerful drug, such as over oxidation, serotonin depletion, dopaminergic neuron damage, etc. [editline]6th May 2015[/editline] [url]http://www.reddit.com/r/DrugNerds/comments/13lp0b/mdma_neurotoxicity_part_1_metabolites/[/url]

[QUOTE=Roll_Program;47670914]Wrong thread. There already is medicinal cannabis anyway. [editline]6th May 2015[/editline] If you take 100mg one off you'll be fine, it only has lasting neurotoxic effects if you're a long term user or taking a large amount in a short period of time.[/QUOTE] People like you make this hard. FDA is unwilling to put cannabis through clinical trials.

[QUOTE=old_hag12;47671348]People like you make this hard. FDA is unwilling to put cannabis through clinical trials.[/QUOTE] It is being put through trials and studies right now, why do you think it's legal in so many states for medicinal use? Old_hag12 please

[QUOTE=Roll_Program;47671446]It is being put through trials and studies right now, why do you think it's legal in so many states for medicinal use? Old_hag12 please[/QUOTE] no, man...