1.6 angstroms resolution(~radius of a single tin atom) snapshots taken with an X-ray laser reveal ho
19 replies, posted
[t]http://i.imgur.com/ToRQF3j.png[/t]
[url]http://www.sciencemag.org/content/346/6214/1242[/url]
[QUOTE]TIME-RESOLVED SERIAL CRYSTALLOGRAPHY CAPTURES HIGH-RESOLUTION INTERMEDIATES OF PHOTOACTIVE YELLOW PROTEIN
Serial femtosecond crystallography using ultrashort pulses from x-ray free electron lasers (XFELs) enables studies of the light-triggered dynamics of biomolecules. We used microcrystals of photoactive yellow protein (a bacterial blue light photoreceptor) as a model system and obtained high-resolution, time-resolved difference electron density maps of excellent quality with strong features; these allowed the determination of structures of reaction intermediates to a resolution of 1.6 angstroms.[B] Our results open the way to the study of reversible and nonreversible biological reactions on time scales as short as femtoseconds [/B]under conditions that maximize the extent of reaction initiation throughout the crystal.[/QUOTE]
Woo! Science!
All I see is that giant Swastika.
[QUOTE=LSK;46655957]All I see is that giant Swastika.[/QUOTE]
This is where we went wrong, all this time we thought they made a moon base, turns out we discovered tiny nazis in our proteins.
pretty fucking cool
[QUOTE=LuckyLuke;46656036]This is where we went wrong, all this time we thought they made a moon base, turns out we discovered tiny nazis in our proteins.[/QUOTE]
They were inside us all along.
[QUOTE=LSK;46655957]All I see is that giant Swastika.[/QUOTE]
I saw loss :v:
These words
[QUOTE=LuckyLuke;46656036]This is where we went wrong, all this time we thought they made a moon base, turns out we discovered tiny nazis in our proteins.[/QUOTE]
Hitler must've stolen the American's Top Secret Magic Schoolbus Technology.
Just that resolution alone and sampling rate can open so many doors for discovering the molecular world and the interactions with it.
That's some serious high resolution bragg-spots. I've got some good brag spots too, but I ain't putting dick pics on the net.
[sp]Oh shit, incoming size jokes[/sp][img]http://www.facepunch.com/fp/ratings/box.png[/img]
*Edit: Doesn't help that bragg-spots are only mentioned in the image, instead of the article.
[QUOTE=wallyroberto_2;46656578]I saw loss :v:[/QUOTE]
I got half way through making a comic where a nerve cell undergoes apoptosis and then I went "why am I spending my Saturday night doing this?"
[QUOTE=Zambies!;46658193]I got half way through making a comic where a nerve cell undergoes apoptosis and then I went "why am I spending my Saturday night doing this?"[/QUOTE]
Making Loss comics is a time-honored tradition, you should be proud.
[QUOTE=WaLLy3K;46657254]That's some serious high resolution bragg-spots. I've got some good brag spots too, but I ain't putting dick pics on the net.
[sp]Oh shit, incoming size jokes[/sp][img]http://www.facepunch.com/fp/ratings/box.png[/img][/QUOTE]
wtf
[QUOTE=WaLLy3K;46657254]That's some serious high resolution bragg-spots. I've got some good brag spots too, but I ain't putting dick pics on the net.
[sp]Oh shit, incoming size jokes[/sp][img]http://www.facepunch.com/fp/ratings/box.png[/img][/QUOTE]
That's because your dick isn't a fact, it's fiction. :v:
[QUOTE=LSK;46655957]All I see is that giant Swastika.[/QUOTE]
nice job
now the discovery has been banned in germany
What can the enlightened ones pass down to the Layman in terms of practical outcomes with this?
I am trying my best here but the paywall isn't cool.
[QUOTE=whatthe;46667652]What can the enlightened ones pass down to the Layman in terms of practical outcomes with this?
I am trying my best here but the paywall isn't cool.[/QUOTE]
We've just figured out how to see fundamental protein structures work (in certain conditions) where we never could before, at [B]insanely[/B] high framerates.
I'm not an expert in any capacity, but I imagine that this should eventually provide massive boosts to the search for cures/treatments for the conditions [URL="http://folding.stanford.edu/"]Folding@Home[/URL] seeks to help by distributing protein-folding simulations (which are incredibly math-intensive): "Alzheimer's, Mad Cow (BSE), CJD, ALS, AIDS, Huntington's, Parkinson's, and many cancers".
And that's just the start, I have no idea what uses will be discovered for this technology. It's able to resolve atomic-level details.
[QUOTE=elixwhitetail;46669216]We've just figured out how to see fundamental protein structures work (in certain conditions) where we never could before, at [B]insanely[/B] high framerates.
I'm not an expert in any capacity, but I imagine that this should eventually provide massive boosts to the search for cures/treatments for the conditions [URL="http://folding.stanford.edu/"]Folding@Home[/URL] seeks to help by distributing protein-folding simulations (which are incredibly math-intensive): "Alzheimer's, Mad Cow (BSE), CJD, ALS, AIDS, Huntington's, Parkinson's, and many cancers".
And that's just the start, I have no idea what uses will be discovered for this technology. It's able to resolve atomic-level details.[/QUOTE]
Fuck! That is mental. Thanks for clearing that up.
And X-ray laser. Free electron laser are so cool, because you can adjust its wavelength/color, which means that laser could theoretically go from radio wave to gamma rays, with the limiting factor are the optics
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