• Down Syndrome Reversed in Newborn Mice with Single Injection
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[img]http://www.abc.net.au/news/image/578392-3x2-340x227.jpg[/img] [quote][B]US researchers have found a way to reverse Down syndrome in newborn lab mice by injecting an experimental compound that causes the brain to grow normally.[/B][/quote] [QUOTE]The compound, which has [B]not been proven safe for use in humans,[/B] is designed to boost normal growth of the brain and body via a gene known as SHH. [B]The gene provides instructions for making a protein called [I]sonic hedgehog[/I], which is essential for development.[/B] We were able to completely normalize growth of the cerebellum through adulthood with that single injection Roger Reeves, Johns Hopkins University School of Medicine "It worked beautifully," said Roger Reeves of the Johns Hopkins University School of Medicine.[/QUOTE] [QUOTE]However, adjusting the [B]treatment for human use would be complicated, since altering the growth of the brain could lead to unintended consequences, such as triggering cancer.[/B] "Down syndrome is very complex and nobody thinks there's going to be a silver bullet that normalises cognition," Dr Reeves said. "Multiple approaches will be needed."[/QUOTE] [url]http://www.abc.net.au/news/2013-09-05/downs-syndrome-reversed-in-newborn-mice/4936412[/url] Bring on the Sonic jokes
gotta go fast
[quote] [B]a protein called [I]sonic hedgehog[/I][/B][/quote] quite simply amazing.
gotta go up
Gotta go normal brain development. But will they suffer the other effects of downs? Like bad hearts and looking like swollen chinese people.
I thought they changed Sonic Hedgehog's name because humorous/pop reference names pissed scientists off
[QUOTE][B][I]protein called sonic hedgehog[/I][/B][/QUOTE] What the fuck.
So that's why all the sonic fans are so attracted to sonic; they never had enough of him in their development, that makes perfect sense.
None of you know of the [URL="http://en.wikipedia.org/wiki/Sonic_hedgehog"]Sonic Hedgehog protein[/URL]?
FYI the enzyme inhibitor for sonic hedgehog is called robotnikin.
Imagine the Sanic Hedgehog protein
[quote]The compound, which has not been proven safe for use in humans,[/quote] So much for that.
[QUOTE=Chubbles;42090301]quite simply amazing.[/QUOTE] dont forget the pokemon gene [url]http://en.wikipedia.org/wiki/Zbtb7[/url]
I'd rather have brain cancer than down syndrome, personally. This is why the ethics on treatment for shit like this is so complicated.
and pikachu [url]http://en.wikipedia.org/wiki/Pikachurin[/url]
There should be a law against naming stuff this stupid.
Surprised nobody's picked up on [url=http://en.wikipedia.org/wiki/Sonic_hedgehog#Robotnikinin]Sonic's inhibitor[/url]
Clear signal that scientists are running out of names.
[QUOTE=duckmaster;42090684]There should be a law against naming stuff this stupid.[/QUOTE] Why? It's much more fun and memorable than the sciency names they usually come up with.
[QUOTE=maurits150;42090700]Clear signal that scientists are running out of names.[/QUOTE] The Sonic Hedgehog has been around, and named such, since the 90s. Sonic Hedhehog's potential inhibitor is also named "Robotnikinin"
[QUOTE=Sir Whoopsalot;42090596]So much for that.[/QUOTE] sounds like theyre still on animal testing, human trials will come later
[QUOTE=IceyMalone;42090587]Imagine the Sanic Hedgehog protein[/QUOTE] that's whats used to give someone downs syndrome
Fucking mice, getting all the health care while we're dying.
Good guy sonic.
"You're Too Slow" [sp] minded [/sp] I'm so sorry
[QUOTE=XanaToast.;42091060]"You're Too Slow" [sp] minded [/sp] I'm so sorry[/QUOTE] You're an asshole I laughed so I'm also an asshole we're all assholes.
[quote]Some clinicians and scientists criticize giving genes frivolous, whimsical, or quirky names, calling it inappropriate that patients with "a serious illness or disability are told that they or their child have a mutation in a gene such as sonic hedgehog."[/quote]
it could start cancer, but what if it mutates the person's genes and gives them a beneficial mutation.
I didn't even bother to think Down syndrome was something that could be reversed.
Comon step it up
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