Potential Male Birth Control Minus the Condoms by 2017 - Polidicks

[quote]Vasalgel, a reversible, non-hormonal polymer that blocks the vas deferens, is about to enter human trials. According to a press release from the Parsemus Foundation, a not-for profit organization focused on developing low-cost medical approaches, Vasalgel is proving effective in a baboon study. Three lucky male baboons were injected with Vasalgel and given unrestricted sexual access to 10 to 15 female baboons each. Despite the fact that they have been monkeying around for six months now, no female baboons have been impregnated. With the success of this animal study and new funding from the David and Lucile Packard Foundation, the Parsemus Foundation is planning to start human trials for Vasalgel next year. According to their FAQ page, they hope to see it on the market by 2017 for, in their words, less than the cost of a flat-screen television. So how does Vasalgel work? It is essentially a reimagining of a medical technology called RISUG (reversible inhibition of sperm under guidance) that was developed by a doctor named Sujoy Guha over 15 years ago in India, where it has been in clinical trials ever since. Unlike most forms of female birth control, Vasalgel is non-hormonal and only requires a single treatment in order to be effective for an extended period of time. Rather than cutting the vas deferens—as would be done in a vasectomy—a Vasalgel procedure involves the injection of a polymer contraceptive directly into the vas deferens. This polymer will then block any sperm that attempt to pass through the tube. At any point, however, the polymer can be flushed out with a second injection if a man wishes to bring his sperm back up to speed.[/quote] I think this is really great news, sure it will be a little harder to protect against STD but this will be most likely marketed towards married couples. SOURCE: [url]http://www.thedailybeast.com/articles/2014/09/09/we-ll-have-male-birth-control-by-2017.html[/url]

So it's pretty much just a reversible vasectomy.

[QUOTE=NixNax123;45942052]So it's pretty much just a reversible vasectomy.[/QUOTE] a hell of a lot more predictable than attempting recanalization and hoping it works, anyway.

That's great, but this won't get a winner until find something better than condoms for STDs. They're the worst ever

I'm still not fond of my balls being injected with something.

I remember reading about this before, sounds like it is going well. I can see there still being pain issues like the vasectomy but of course this is reversible now so that isnt nearly as terrible.

[QUOTE=Rhenae;45942086]I remember reading about this before, sounds like it is going well. I can see there still being pain issues like the vasectomy but of course this is reversible now so that isnt nearly as terrible.[/QUOTE] Eh, pain is a small price to pay to help prevent unplanned pregnancies. This will p.much revolutionize birth control as it currently is. ouch, my mistake. I forgot about long-term complications.

[QUOTE=Zonesylvania;45942102]Eh, pain is a small price to pay to help prevent unplanned pregnancies. This will p.much revolutionize birth control as it currently is.[/QUOTE] You may have just misread my post, but if not go look up the plausible after effects of vasectomy, because thats what im refering to. The percentages are quite high for some serious long term pain which isnt necessarily reversible.

Where does all the blocked sperm go when "the vas deferens" or the "sperm tube" is blocked? (Let alone cut in a vasectomy, and tied in a knot, or w/e?) [editline]10th September 2014[/editline] Doesn't it create a clog in the pipes, causing it to potentially burst?

[QUOTE=Bat-shit;45942157]Where does all the blocked sperm go when "the vas deferens" or the "sperm tube" is blocked? (Let alone cut in vasectomy, and tied in a knot, or w/e?)[/QUOTE] It remains inside the testicle, and subsequently gets broken down as time passes. As for the rest; after vasectomy, the membranes of the seminiferous tubules must increase to store and hold the seminal fluid, which in turn triggers macrophages to absorb the broken down leftovers. Sometimes this can lead to the formation of a sperm granuloma (a mass of broken down sperm) which gets treated like a foreign object by the immune system and may induce permanent infertility if the reaction is severe enough.

[QUOTE=Bat-shit;45942157]Where does all the blocked sperm go when "the vas deferens" or the "sperm tube" is blocked? (Let alone cut in a vasectomy, and tied in a knot, or w/e?) [editline]10th September 2014[/editline] Doesn't it create a clog in the pipes, causing it to potentially burst?[/QUOTE] No. It just doesn't go anywhere. Thank god my girlfriend needs the pill to balance her hormones, seriously, I'm not not letting anyone inject my sack, the amount of fucking times nurses and doctors miss my veins worries me about if they miss down there.. And it could be a lot more detrimental..

[QUOTE=Zonesylvania;45942181]It remains inside the testicle, and subsequently gets broken down as time passes. As for the rest; after vasectomy, the membranes of the seminiferous tubules must increase to store and hold the seminal fluid, which in turn triggers macrophages to absorb the broken down leftovers.[/QUOTE] Sounds like awful blue balls

That's pretty neat. Although I've heard about some kind of implants that also work pretty well.

[QUOTE=Zonesylvania;45942181]It remains inside the testicle, and subsequently gets broken down as time passes.[/QUOTE] Sounds like the testicles are constantly stuffed then, I mean if the production of sperm doesn't end and nothing ever gets out? Do people find this an issue maybe, like pain or discomfort?

[QUOTE=Bat-shit;45942208]Sounds like the testicles are constantly stuffed then, I mean if the production of sperm doesn't end and nothing ever gets out? Do people find this an issue maybe, like pain or discomfort?[/QUOTE] Post-vasectomy pain syndrome can sometimes result because of fibrous tissue trapping nerves as it grows to heal the wound. Sometimes the scar tissue can be disrupted if enough pressure is exerted by whatever is in there. Sometimes this can lead to cyst formation holding seminal fluid/broken down semen. Note that this doesn't happen in all cases.

[QUOTE=Zonesylvania;45942217]Post-vasectomy pain syndrome can sometimes result because of fibrous tissue trapping nerves as it grows to heal the wound. Sometimes the scar tissue can be disrupted if enough pressure is exerted by whatever is in there. Sometimes this can lead to cyst formation holding seminal fluid/broken down semen. Note that this doesn't happen in all cases.[/QUOTE] If this is the risk of such an injection, shouldn't there be much more rigorous testing to find a mean percentage of side effects before human trials? I mean aiming for 2017 seems like they're rushing it.

[QUOTE=Tasm;45942219]If this is the risk of such an injection, shouldn't there be much more rigorous testing to find a mean percentage of side effects before human trials? I mean aiming for 2017 seems like they're rushing it.[/QUOTE] This won't apply to this new method because there won't be any surgical wound, and thus no scar for there to be scar tissue formation. This is what happens with the current method of vasectomy, not the new one.

Is this that same thing that shrunk the testicles of the rats they were testing it on?

[QUOTE=Code3Response;45942072]I'm still not fond of my balls being injected with something.[/QUOTE] I don't think it would be injected in the wa you're thinking, I think it would more be inserted though the existing holes though something like a catheter Far worse then what your thinking

[QUOTE=Zonesylvania;45942263]This won't apply to this new method because there won't be any surgical wound, and thus no scar for there to be scar tissue formation. This is what happens with the current method of vasectomy, not the new one.[/QUOTE] By the way, would you have any knowledge of what may happen to the plumbing down there if there isn't a release every so often? Because as we all know if you don't release regularly, a wet dream will take care of the job. Are there any risks associated with not ejaculating sperm for long periods of time that you know of?

injection in to balls? i'll take my chances :v:

Do I come puffs of air and can I opt for it to sound like a steam whistle?

[QUOTE=Tasm;45942356]By the way, would you have any knowledge of what may happen to the plumbing down there if there isn't a release every so often? Because as we all know if you don't release regularly, a wet dream will take care of the job. Are there any risks associated with not ejaculating sperm for long periods of time that you know of?[/QUOTE] No such risks, it can be left as such for a fairly long haul without surgeries, nor will it affect anything if the operation is carried out. No harm really.

[QUOTE]Three lucky male baboons were injected with Vasalgel and given unrestricted sexual access to 10 to 15 female baboons each. [/QUOTE] Where do I sign up for human testing

[QUOTE=Coment;45942386]Where do I sign up for human testing[/QUOTE] The study will apparently start up next year since the animal study was successful.

[QUOTE=Bat-shit;45942208]Sounds like the testicles are constantly stuffed then, I mean if the production of sperm doesn't end and nothing ever gets out? Do people find this an issue maybe, like pain or discomfort?[/QUOTE] It's the same as if a blood vessel pops or is ruptured and you get a bruise, the body just reabsorbs it.

[QUOTE=Coment;45942386]Where do I sign up for human testing[/QUOTE] Humans can't impregnate baboons, nice try.

[QUOTE=Zonesylvania;45942181]It remains inside the testicle, and subsequently gets broken down as time passes.[/QUOTE] [QUOTE=Tasm;45942198]No. It just doesn't go anywhere.[/QUOTE] Other articles and the [URL=http://www.ncbi.nlm.nih.gov/pubmed/15192063]original research[/url] don't suggest that at all, they say that it's a chemical method for destroying the cells as they pass without blockage. Where are you getting that it's an artificial blockage?

[QUOTE=catbarf;45942448]Other articles and the [URL=http://www.ncbi.nlm.nih.gov/pubmed/15192063]original research[/url] don't suggest that at all, they say that it's a chemical method for destroying the cells as they pass without blockage. Where are you getting that it's an artificial blockage?[/QUOTE] We were talking about the sperm itself, not the gel.

[QUOTE=proch;45942202]That's pretty neat. Although I've heard about some kind of implants that also work pretty well.[/QUOTE] Yeah, it's called Implanon. Pretty neat! (it's for girls, so I don't feel the pain and don't have to remind a certain person to take the pill :v:)