This is a revival of Love's locked DMX thread(Yes it is a copy paste):
What it is
DXM hbr (short for "dextromethorphan hydrobromide") is a drug found in OTC ("over the counter") cough medicines. In small, medically recommended doses, it acts as an "antitussive" and restricts the body's cough reflex. At higher doses (anywhere from 5 to 50+ times the normal dose) it acts as a dissociative hallucinogenic drug with effects similar to ketamine and PCP (two drugs which are very illegal to use recreationally.) Nothing terribly special compared to other drugs really, until you consider the fact that DXM as a recreational substance is almost completely uncontrolled, especially in the US.
DXM can be found in more than 140 cough and cold medications available without a prescription. What this means, basically, is that you can walk into almost any store with about ten dollars, take a stroll through the medicine aisle, and leave with enough pills to (relatively safely) trip balls for about eight hours.
Where to get it
Ideally, if you're planning on chugging syrup, get it from Walgreens. They have grape and orange flavored store brands which contain no menthol, no medicines other than DXM hbr, and a fairly potent 15mg of dxm per 5ml of syrup. Walgreens also carries gelcaps and Zicam MAX containing dxm. Alternatively, syrups, gels, and Zimax can be purchased at places like King-Soopers, CVS, Wal-Mart, Safeway, etc. etc.
DXM can also be purchased from some drug dealers, either after it has been extracted, or in pure powder form. I've heard that some online pharmaceutical manufacturers sell pure powdered DXM in bulk, but A) Taking powdered DXM results in much faster absorption, which makes for a harder and sometimes less enjoyable trip, B) Powdered DXM can also be difficult to measure properly. With gelcaps and syrups you'll always know exactly how much you're getting, and C) I have no idea where you'd need to go to purchase DXM online. For the sake of simplicity, I'll mostly be sticking to the store-bought methods of using DXM.
(OR, you can try buying powdered DXM from online supplier [url]www.ldfifty.net[/url]. (Thanks, joe588))
What to Expect/How to do it: Dosage
When you get into dosages of DXM things can get complicated, and this is the main reason I'm making this thread, so pay special attention here if you're planning on using DXM. Some people may tell you to simply "Chug a bottle of cough syrup" to get high, but "a bottle" is a useless unit of measurement with DXM. This is because, depending on the bottle you grab, DXM content can range anywhere from more than 700mg to less than 120mg. If you want to use DXM intelligently, figure out your body weight in KG, learn to multiply/divide, and get used to reading "active ingredient" labels and paying attention to bottle sizes.
I'll begin with the "plateaus." DXM trips are divided up into four different plateaus of effects based on how much DXM you take and how many KG you weigh.
* 1st Plateau: 1.5 to 2.5 mg/kg (100-170mg for a 150lb (68kg) person)
You'll have a slightly intoxicated, light headed feeling and will be distracted easier. Your mind will wander more freely and you will experience slight music induced euphoria.
* 2nd Plateau: 2.5 to 7.5 mg/kg (170-500mg for a 150lb (68kg) person)
Similar to being stoned and drunk. Heightened music euphoria (if you like music, you'll LOVE music on this dose.) Mild hallucinations, especially with eyes closed.
You may have a trouble chatting due to slight confusion and will probably be slurring words. Short-term memory loss is not uncommon at this dose, and will likely be impaired (yet another reason why in-depth conversations may be difficult.)
* 3rd Plateau: 7.5 to 15 mg/kg (500-1000mg for a 150lb (68kg) person)
Very intoxicating, strong hallucinations, especially CEV's (Closed Eye Visuals.) Things may be become very confusing as your thinking processes are disturbed. For example, you'll get lost easier if you're walking around, you may wonder how you ended up in the room you're in (even if you've been there for hours) and timelines become distorted ("Wait, when did we get here?" or "How long has that dog been here?") You'll have intense hallucinations and CEV's in dark spaces and will be able to daze-off into your own world, and get lost in your own mind. Third plateau trips can be unpleasant for an inexperienced drug user, but wildly gratifying for anyone looking to get fucked up and have a good time doing it.
* 4th Plateau: 15 to (LESS THAN) 20 mg/kg (1000-1300mg for a 150lb (68kg) person)
This is a sub-anesthetic dose, similar to taking a high dose of Ketamine. Your mind and body become seperated at this level and it can become dangerous psychologically, and physically. You should probably never go this high, as it can be very dangerous. If you do dose this high, it's wise to have a sober someone, preferably someone experienced with DXM, nearby in case you start to feel legitimately like you're going to die.
* -DEATH: 20+ mg/kg (1360+mg for a 150lb (68kg) person)
This is the point at which a dose of DXM becomes very toxic and kills you.
Now, what is this mg/kg you keep seeing?
"8mg/kg" is another way of saying "eight milligrams of DXM per kilogram of body weight"
What this means is, if you weigh 68kg (about 150 pounds), you'll multiply that by eight (68 x 8 = 544), and that number (544mg) is the amount of DXM a 68kg person would need to ingest to get 8mg/kg (a low 3rd plateau trip) in his system.
To get your weight in KG from pounds, divide your weight in pounds by 2.2. (Or if you don't feel comfortable doing that, use this online calculator.)
If you have any questions about the dose you should take, don't hesitate to post and ask here.
How to do it: Medicine types
When you go to purchase your DXM, there are a few things you need to consider when picking out a medicine. Note that if you are under 18 you may be unable to purchase any medicine containing DXM.
The most important thing you need to look for is the "Active Ingredient" tab on the medicine's label. Ideally, you want to see "Dextropethorphan HBr, 15 mg ... cough suppressant" as the ONLY ingredient. Guaifenesin is a secondary ingredient in many cough syrups and won't cause immediate harm to you, even in large doses, but will likely make you throw up. Other ingredients like decongestants, antihistamines, and analgesics (painkillers like acetaminophen/paracetamol) at these higher doses WILL destroy your liver and kill you, so avoid recreationally using medicines with these drugs at all costs.
Second, decide how you want to take your DXM. Your three main options are gelcaps, syrups, and throat spray:
* Gelcaps: Although gels aren't the most economical option, after over a year of using DXM I've found gel-caps to be the easiest, and simplest, store-bought option. Gelcaps come in bottles of 20.. and with 15mg of dxm per gel, that's 300mg per bottle.
* Syrups: The cheapest and most readily available option. Always pay close attention and read the active ingredient list before you use syrups. Usually, syrup potency is 15, 10, or 5mg of DXM per 5ml of syrup. You want that number to be as high as possible, as a higher number means less chugging to get your DXM, so shoot for 15mg/5ml. Syrups containing menthol can cause nausea.
* Throat Spray: "Zicam Cough MAX" contains 390mg of dxm in an amount of liquid smaller than a single shot. Its taste is ungodly, but that's the price you pay for such a high concentration of DXM.
* Delsym "12-hour relief": A different sort of DXM
"Dextromethorphan polistirex equivalent to 30mg dextromethorphan hydrobromide" per 5/ml:
Delsym contains dextromethorphan "polistirex," which absorbs differently from dextromethorphan "hydrobromide."
Basically, the "polistirex" part means that the microscopic particles of dxm have been coated in an edible plastic coating, making the medicine take longer to absorb into the body as well as making it last longer than the usual "hydrobromide." I don't have a lot of experience with DXM polistirex, but the few times I've tried it, I was disappointed, because taking 900mg of DXM poli feels about the same as taking 300-450mg of DXM hbr and stretches it out about 1.5 times the normal length of a trip.
Most Delsym bottles contain 145ml. At 30mg DXM hbr equivalent per 5ml, the entire bottle has 870mg of DXM in it. This means, if you're 150 pounds (about 68kg) the entire bottle would normally be just under 13mg/kg. However, since it's poli instead of hbr, you'll probably feel more like you've taken 4-7mg/kg and it'll last hours longer than you may be used to.
Unless DXM poli is your only option, I'd recommend simply sticking to hbr instead of poli. (Remember to always look at the active ingredients on the back of the box before you dose. An initial clue as to what contains poli instead of DXM can usually be found on the front of the box: look for a slogan like "8 hour relief" instead of "12 hour relief," as the 12 hour is usually DXM polistirex, and 8 hour is DXM hbr.)
And finally.. AVOID DXM if you've taken any sort of antidepressant drug (MAOI, TCA, SSRI, SNRI, etc), as DXM may interact with these drugs and cause serotonin syndrome.
Also, don't drink alcohol heavily, if at all, while you're on DXM. Dex + alcohol will often = lots of puking, trembling, undesirably extreme confusion and generally having a lousy experience likely ending with a hospital visit.
This thread just contains the very basics, I recommend reading more about the drug if you're interested. There are pages upon pages of knowledge pertaining to DXM, so stay informed. I got most of my info from the dextroverse, and they have a far more in-depth FAQ for anyone interested in learning more about the drug.
[editline]10:47AM[/editline]
And just take this tip from me, if your doing cough syrup, pour it into a large glass of Mnt Dew of coffee, most likely the caffeine will accelerate your high. And it makes it easy to drink.
Shoulda let Love re make it... Cus this doesn't look too great for my eyes, with nothing highlighted/put in bold. Sort it out or Love make a new one. :dance:
[QUOTE=Imalegend;16219656]Shoulda let Love re make it... Cus this doesn't look too great for my eyes, with nothing highlighted/put in bold. Sort it out or Love make a new one. :dance:[/QUOTE]
Ill sort it out
Posting information about drug interactions could be helpful. I'm pretty sure you wouldn't want to take it if you were drunk.
Ok ill add that info.
[editline]04:24PM[/editline]
Fatal or Dangerous Interactions
DXM should not be used (either recreationally or at normal dosage levels) by people who are taking a monoamine oxidase inhibitor (MAOI, rhymes with "wowee") - either a prescription MAOI or a recreational one such as harmaline. Note that there is considerable confusion among drug users about what is and isn't a MAOI. MAOIs include a few drugs prescribed for depression and Parkinson's disease, and a few rare recreational drugs derived from exotic plant sources (harmine and harmaline, from Syrian Rue and Yagé, for example). ProzacTM, MDMA, cheese, beer, SeldaneTM, etc., are not MAOIs - they are things to avoid when taking a MAOI. If you are taking a prescription MAOI you will almost certainly know, as your physician will have (hopefully!) told you to avoid eating aged cheeses. Combining DXM and a MAOI has been fatal (3)!
Fluoxetine (ProzacTM) is a cytochrome P450-2D6 inhibitor (39) and will change the characteristics of a DXM trip somewhat, increasing the ratio of DXM to DXO. Other P450-2D6 inhibiting drugs, which include many antidepressants, will probably do the same; see Section 15.1. The duration of the trip may be greatly extended by P450-2D6 inhibitors; some users have reported effects lasting 12 to 24 hours past the normal duration. The potency of DXM may also be enhanced via other mechanisms by fluoxetine (40).
Combining DXM with the antidepressants Desyrel (trazodone) or Serzone (nefazodone) has been reported to cause liver damage!
One user reported that combining DXM with bupropion (Wellbutrin[tm]) resulted in a prolonged (3+ day) hangover and an increase in adverse side effects.
Fluoxetine and other SSRI antidepressants, as well as tricyclics and lithium (and of course MAOIs) may interact with DXM to cause serotonin syndrome. This condition, although rarely fatal, is not terribly pleasant. Vascular disease may increase the chance for serotonin syndrome with DXM + antidepressants (364), and other disease conditions may do so as well. Some DXM users who have taken DXM while on antidepressants have reported unpleasant reactions that sound a lot like serotonin syndrome, so you might want to watch out. Some of the symptoms of serotonin syndrome include muscle rigidity, confusion, diarrhea, incoordination, low-grade fever, sweating, muscle tremor, mania, agitation, exaggerated reflexes, and nausea.
Do not take DXM with the diet drugs phentermine, fenfluramine, or phen-fen; this combination can also cause serotonin syndrome.
DXM should not be taken (recreationally or at normal dosage levels) with the prescription antihistamine terfenadine (SeldaneTM). This combination has been fatal (41). Terfenadine has been implicated in other drug interactions, incidentally. The reason for this interaction seems to be that terfenadine, which is normally metabolized by a P450 enzyme, induces heart irregularities when it builds up. DXM may saturate the P450 enzymes that normally metabolize terfenadine. Incidentally, this probably applies to other non-drowsy antihistamines, such as ClaritinTM and HisminalTM as well; avoid combining them with DXM.
Some people find that nicotine (cigarettes) causes severe nausea when combined with DXM. Others have noticed a general increase in physical discomfort and "bad trips" from combining the two. Some research has suggested that cigarette smoke inhibits monoamine oxidase (378,379) in which case cigarettes could greatly increase the chance of unpleasant side effects.
[editline]04:26PM[/editline]
Both opiates and dissociatives have strong side effects which can limit their usefulness in pain treatment. When the two are combined, however, a synergistic effect occurs, and patients can lower the dose of both drugs to the point where side effects are minimalized (236,267,278). Dissociatives prevent tolerance to opiates (248) and can alleviate opiate withdrawal (254). On the other hand, combining the two may increase the chance for respiratory depression and fatal overdose.
[editline]04:26PM[/editline]
Marijauna and DXM is a frequently used combination, albeit one which has seen little research. Competitive NMDA blockade enhances marijuana catalepsy (210), and conceivably noncompetitive blockade would as well. Dizocilpine, a dissociative used in research, decreases the analgesic effects of marijuana (214), and causes downregulation of anandamide receptors (THC receptors) (218).
Dissociatives may block the depletion of 5HT (serotonin) caused by MDMA (ecstasy) (241). However, there is also the potential for hypertensive problems, so I wouldn't advise this combination. Methamphetamine produces vacuolation of neuron terminals due to a collapsed vesicular proton gradient (181) (translated into English, this means that speed damages brain cells by breaking open the little bubbles of neurotransmitters inside the cells). However, dizocilpine (and presumably other dissociatives) may prevent this (219). It also seems to block methamphetamine induced 5HT depletion (241).
Antidepressants and dissociatives seem to interact as well, not necessarily in a good way. Both desipramine and dissociatives increase prefrontal lobe dopamine activity; the combination is highly synergistic (277). Even worse, dissociatives may actually reverse the antidepressant effect (229). Dizocilpine reduces 5HT2 receptor density (212), and increases 5HT binding in the hippocampus and striatum (252). On the other hand, one paper found that dizocilpine helped antidepressants in some tests (245,250).
Finally, dissociatives block tolerance to many drugs, including alcohol (232), cocaine (247), nicotine (249), and morphine (248).
You spelled DXM wrong in the thread title...
Great thread though. Thanks.
Oh, i was dexing while i made it, sorry about that. And thanks. Their are other drugs like DXM that are found OTC, i might make threads for them if i can find info.
[editline]05:59PM[/editline]
Just checking to see if my dosages are right, I weigh 110 pounds divide by 2.2 is 50kg and its 3mg/kg at 10mg/5ml, so 3*5=150mg, 150/5=30ml needed for mid 2nd plateo?
I think love should make the new dxm just cause its tradition :3
His has been down for almost a week, and my friend is robotripping for the first with me tomorrow, he needs the info on the front page. That and mine has a little more info. After this thread gets locked ill only post on how to meditate on DXM.
love asked me to close that thread personally. So if you want to make a thread on DMX(X gon give it to ya) then rewrite it yourself
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