Lithium profoundly prevents brain damage associated with Parkinson's disease - Polidicks

[release] [b]Lithium profoundly prevents the aggregation of toxic proteins and cell loss associated with Parkinson's disease (PD) in a mouse model of the condition. [/b] Preclinical research is now underway at the Buck Institute for Research on Aging to determine correct dosages for a drug that continues to be the gold standard for the treatment of bipolar disorder. The Buck is currently working toward initiating a Phase IIa clinical studies of lithium in humans in conjunction with standard PD drug therapy. The research appears in the June 24 online edition of the Journal of Neuroscience Research. "This is the first time lithium has been tested in an animal model of PD," said lead author and Buck Professor Julie Andersen, PhD. "The fact that lithium's safety profile in humans is well understood greatly reduces trial risk and lowers a significant hurdle to getting it into the clinic." According to Andersen, lithium has recently been suggested to be neuroprotective in relation to several neurodegenerative conditions including Alzheimer's disease, Huntington's disease and amyotrophic lateral sclerosis and has been touted for its anti-aging properties in simple animals. "We fed our mice levels of lithium that were at the low end of the therapeutic range," said Andersen. "The possibility that lithium could be effective in PD patients at subclinical levels is exciting, because it would avoid many side effects associated at the higher dose range." Overuse of lithium has been linked to hyperthyroidism and kidney toxicity. PD is a progressive, incurable neurodegenerative disorder that affects 1 million Americans and results in tremor, slowness of movement and rigidity. It is the second most common neurodegenerative disease after Alzheimer's. Between 50,000 and 60,000 new cases are diagnosed each year. Age is the largest risk factor for the PD. Onset usually begins between the ages of 45 and 70 years. Andersen's research focuses on lithium as a potential treatment for PD as well as its efficacy in combination with drugs currently used to control the symptoms of the disease. An internet search reveals stories from PD patients who are using lithium "off label" as part of their treatment regime; others report benefits from low dose lithium salts which are available as a supplement in some health food stores. "This finding gives us an opportunity to explore lithium as a recognized therapeutic for PD, in doses that are safe and effective" said Andersen.[/release] [url=http://medicalxpress.com/news/2011-06-lithium-profoundly-brain-parkinson-disease.html]Source[/url]

I knew eating those batteries was a good idea!

I wonder how this would factor into adding Lithium to the public water supply.

Wow, and here my ignorance thought it'd kill you!

[QUOTE=Thy Reaper;30692067]I wonder how this would factor into adding Lithium to the public water supply.[/QUOTE] If the majority of the public had Parkinson's it would likely be something to consider But as it stands using this as an argument for putting Lithium in the water is like using cancer as an argument for putting chemo drugs in the water

[QUOTE=Zeke129;30692114]If the majority of the public had Parkinson's it would likely be something to consider But as it stands using this as an argument for putting Lithium in the water is like using cancer as an argument for putting chemo drugs in the water[/QUOTE] Chemo drugs are cytotoxic, Lithium is harmless.

[QUOTE=Helix Alioth;30692236]Chemo drugs are cytotoxic, Lithium is harmless.[/QUOTE] It's not harmless when overused

putting mood stabilisers in the water supply is a terrible idea

[QUOTE=Zeke129;30692251]It's not harmless when overused[/QUOTE] While I disagree with the notion of adding lithium to water supplies, I highly doubt that the concentrations used would be great enough to cause issues. They'd account for the people who consume large amounts of water, as well as infants. (If not wow)

well hey they already put fluoride in the water

They put something in the water to make us forge.... remember.

Lithium is a micronutrient as is, so I don't think adding it to water would be a bad idea so long as it is done in extremely small quantities.

[QUOTE=Edgar Allan Poe;30692570]Lithium is a micronutrient as is, so I don't think adding it to water would be a bad idea so long as it is done in extremely small quantities.[/QUOTE] Florine is already in small quantities, and has shown it's helpfulness, so has chlorine, and other chemicals that are saving lives. But people keep bitching that they want their water "Pure as nature intended" Good luck with your diarrhea hippies

The NWO makes yet another move to further poison us! Wake up you sheeple! :tinfoil:

[QUOTE=DesolateGrun;30693196]Florine is already in small quantities, and has shown it's helpfulness, so has chlorine, and other chemicals that are saving lives. But people keep bitching that they want their water "Pure as nature intended" Good luck with your diarrhea hippies[/QUOTE] the sad part is lithium is naturally occurring :v:

[QUOTE=Zeke129;30692251]It's not harmless when overused[/QUOTE] Nothing is harmless when overused. I mean, hell, WATER and OXYGEN will fucking [i]kill[/i] you if there's too much.

[QUOTE=Zeke129;30692251]It's not harmless when overused[/QUOTE] The only people who carry a risk of detrimental effect due to lithium (re)dissolved into drinking water are those who are on lithium treatments, as they are taking doses just below poisoning risk. [QUOTE=Mon;30693455]the sad part is lithium is naturally occurring :v:[/QUOTE] [URL="http://www.ags.gov.ab.ca/publications/abstracts/DIG_2010_0001.html"]At possibly much higher amounts than they will be putting in, too.[/URL]

[QUOTE=Mattk50;30692515]well hey they already put fluoride in the water[/QUOTE] Fluoride doesn't alter your mindset [editline]24th June 2011[/editline] [QUOTE=ExplodingGuy;30694169] [URL="http://www.ags.gov.ab.ca/publications/abstracts/DIG_2010_0001.html"]At possibly much higher amounts than they will be putting in, too.[/URL][/QUOTE] Alberta is completely retarded so I'm not surprised there's stuff in the water

QUICK SOMEBODY GET THIS TO MICHAEL J. FOX. c

[QUOTE=Zeke129;30694243]Fluoride doesn't alter your mindset [editline]24th June 2011[/editline] Alberta is completely retarded so I'm not surprised there's stuff in the water[/QUOTE] Lithium does nice things like prevent brain damage and it's still bad alright

[QUOTE=Zeke129;30694243]Fluoride doesn't alter your mindset[/QUOTE] I'm curious: As there are locations in which there is a significant amount of lithium already present in the water supply, would you prefer it be removed? Which is the 'correct' natural state, naturally present lithium, or naturally absent lithium? Given that both states alter brain chemistry, what basis do you have to say that we should prefer lacking it?

This is good.

[QUOTE=Thy Reaper;30694388]I'm curious: As there are locations in which there is a significant amount of lithium already present in the water supply, would you prefer it be removed? Which is the 'correct' natural state, naturally present lithium, or naturally absent lithium? Given that both states alter brain chemistry, what basis do you have to say that we should prefer lacking it?[/QUOTE] he doesn't like the part where the government does anything to help people out

lithium can also be used as a schizophrenia treatment

[QUOTE=Tetracycline;30694467]he doesn't like the part where the government does anything to help people out[/QUOTE] Not without their consent, no Especially not without further research

[QUOTE=Dippeggs;30691887]I knew eating those batteries was a good idea![/QUOTE] dont lick a 9 volt

fuck its not like they're talking about putting lamotrigine in the water or something

I think this would be good, some people seem to think lithium is the equivalent of anti-depressants and we'll all turn into mindless zombies. As far as i know people without schizophrenia and parkisons aren't classed as zombies.

[QUOTE=Gareth;30697351]I think this would be good, some people seem to think lithium is the equivalent of anti-depressants and we'll all turn into mindless zombies. As far as i know people without schizophrenia and parkisons aren't classed as zombies.[/QUOTE] as far as I know mood altering drugs shouldn't be forced on people who don't need them. You do realize that these things change the way you act right? That doesn't bother you at all?

[QUOTE=Thy Reaper;30694388]I'm curious: As there are locations in which there is a significant amount of lithium already present in the water supply, would you prefer it be removed? Which is the 'correct' natural state, naturally present lithium, or naturally absent lithium? Given that both states alter brain chemistry, what basis do you have to say that we should prefer lacking it?[/QUOTE] Still waiting for a response to this Zeke, should be a simple question. [editline]25th June 2011[/editline] [QUOTE=Rofl my Waff;30697486]as far as I know mood altering drugs shouldn't be forced on people who don't need them. You do realize that these things change the way you act right? That doesn't bother you at all?[/QUOTE] Same question to you. There are chemicals in everything, and many are necessary to different levels. What do you know that demonstrates no Lithium to be healthier than Lithium, given that either level presents a different brain chemistry?