Do something in paint, and then do the same thing or repeat on top in photoshop, or vice versa.
[img]http://www.deviantart.com/download/135342618/Photoshop_vs_M__Paint_by_fadingz.jpg[/img]
First painted in M$ Paint, then edited a bit in Photoshop (repainted actually lol)
here's the comparison.
I post both once I'm done with the photoshop one.
Here's the one done in M$ Paint regardless:
[url=http://fadingz.deviantart.com/art/Samus-Aran-M-Paint-135247232#][img]http://th06.deviantart.net/fs28/300W/i/2009/241/b/c/Samus_Aran_M__Paint_by_fadingz.jpg[/img][/url]<- click to dA link for larger image