Few treatment options are available to people facing a second battle with a particularly fatal type of brain tumor called glioblastoma. But dosing the tumor with a genetically modified poliovirus — one that doesn’t cause the eponymous, devastating disease — may give these patients more time, a small clinical study suggests.
Of 61 people with recurring glioblastoma who were treated with the modified virus, 21 percent were alive after three years. In a “historical” comparison group of 104 patients, who would have been eligible for the treatment but died before it was available, 4 percent lived as long, researchers report online June 26 in the New England Journal of Medicine.
Both people who have survived for six years developed glioblastoma again, but were successfully treated a second time with the altered poliovirus. “There doesn’t seem to be any resistance to re-treatment,” Bigner says.
Poliovirus treatment helped patients with deadly brain tumors li..
still learning how to format from a phone but this was an interesting piece I came across. Its not a cure but the way they combined polio with the common cold to both attach to, attack, and trigger an immune response to the tumor seems really amazing and also scary
Makes sense, given that polio in nature is neuropathogenic.
I think my favorite oncolytic virus is herpes simplex virus, because if that works out, then it'd just be fun to say "Hey, I need to go get herpes to deal with my cancer."
Is this a "villain redeems himself" arc?
In all seriousness this is fucking awesome.
Neat study, my professor bought it up when we were discussing the lytic cycle. I bet it went real smooth when the doctors unveiled this to their patients.
"Doc, what are you doing for my brain cancer?"
"It's simple, really. We're putting polio in your tumors."
Oh my god
The anti vaxxers were right all along
/s
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