• What Happens When CRISPR Backfires?
    8 replies, posted
https://www.youtube.com/watch?v=8b_d3RIJJmo
Can't even imagine the crazy shit that's been going down in China in the area of human clinical trials. They have the money and brainpower to match the USA, without all the ethical concerns that surround human trials.
I wonder how long it will be before we hear about the horrors going on over there.
its taking actual microorganism 'tech' and trying to apply it to a scale thousands of times larger. what do you expect the human body is really really good at preventing dna from just getting snipped without repercussion. the protein she mentioned (p53) is what immediately notices and repairs the snipping, among many other factors. without it, crispr 'works', but it also means that there are failsafes missing from that cell (again, as she mentioned) and it'll probably be a cancerous cell later the hype behind crispr is a huge letdown - i read that, basically in a lot of studies on smaller organisms where this was applied (like rats), there was no long term effects analyzed because a lot of the subjects were terminated early on purpose. that kind of shit data is arrogant and purposely misleading
I question if we ever will know. Like their organ harvesting vans, they're probably subjecting all of this on political opponents, religious/ethnic minorities, and anyone else the goverment doesn't approve of. Once they get taken away, you will never hear from any of them again. I bet they cremate all the corpses too.
For myself, the greatest possibility for CRISPR will be modifying the genes of wild/farmed animals, in order to aid their existence. One great idea is using it to help coral reefs be more resiliant to climate change caused by humans. Likewise, we could also use CRISPR for gene-edits on farmed/stocked fish species. Not only would this allow us to deal with certain viruses and parasites, but it could also open the door for farming fish species which have been otherwise a pain in the ass to farm. Think tuna and sharks. People could get their sushi or fin-soup fix, but we could farm said creatures and not have nearly as much damage on wild ecosystems. Using CRISPR for simply gene-modding humans would be utterly wasteful of such a fantastic technology, and it would ultimately lead it down a road of being heavily regulated to prevent people from going full retard.
Doesn't CRISPR already have a successor though?
I'm looking forward to have modified plants where they scream all day and night at a farm and screams when the farmer uproots them If possible make them swear at humans
Culling rats is an ethical decision. If they were killed early it's because the experiment was over, they weren't measuring for long term effects. It costs time and money to run experiments and means you plan for when they need to end. Nobody claims that there are no long term effects beyond the length of the experiment when they do this.
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