How A Gene Editing Tool Went From Labs To A Middle-School Classroom - Sensationalist Headlines

[QUOTE]On a Saturday afternoon, 10 students gather at Genspace, a community lab in Brooklyn, to learn how to edit genes. There's a recent graduate with a master's in plant biology, a high school student who started a synthetic biology club, a medical student, an eighth grader, and someone who works in pharmaceutical advertising.[/QUOTE] [URL="http://www.npr.org/sections/alltechconsidered/2017/05/27/530210657/how-a-gene-editing-tool-went-from-labs-to-a-middle-school-classroom"]http://www.npr.org/sections/alltechconsidered/2017/05/27/530210657/how-a-gene-editing-tool-went-from-labs-to-a-middle-school-classroom[/URL] Gene editing is seemed now spreading to every school in this country.

[QUOTE=ChadMcGoatMan;52283857]And Furry Revolution here we come.[/QUOTE]I would think you of all people here would be familiar with [url=http://us.vclart.net/vcl/Authors/Will-A.-Sanborn/General/FAILURE.htm]this story.[/url]

[QUOTE=Sgt Doom;52283868]I would think you of all people here would be familiar with [url=http://us.vclart.net/vcl/Authors/Will-A.-Sanborn/General/FAILURE.htm]this story.[/url][/QUOTE] Ok, Nice emotional short story from that Furry site. But this story made from [I]19th years ago[/I] (author published this in late 1996) so it's feel dated to today standards and gene editing were still it's limited with crispr-9 itself already discovered but isn't named yet back then, But it's so really makes sense for explains genetic error center plot point from story.

[QUOTE=ChadMcGoatMan;52283886]Ok, Nice emotional story from that Furry site. But this story made from [I]19th years ago[/I] (author published this in late 1996) so it's feel dated to today standards and gene editing were still it's limited with crispr-9 itself already discovered but isn't named yet back then, But it's so really makes sense for explains genetic error center plot point from story.[/QUOTE]Are you under the impression that such radical, heretofore untried experimentation of merging entirely different species to create a new, sapient one, would be error-free just because of modern techniques? It's fairly easy to shrug off buggering up editing the e. coli genome, but quite a different ethical beast when what you're editing is intended to, or has, self-awareness. It's essentially condemning potentially many dozens of sapient beings to a dreadful, malformed existence for no better reason than getting your yiff on. We're not at the point where computer simulations suffice to get it perfect right off the bat.

[QUOTE=Sgt Doom;52283903]Are you under the impression that such radical, heretofore untried experimentation of merging entirely different species to create a new, sapient one, would be error-free just because of modern techniques? It's fairly easy to shrug off buggering up editing the e. coli genome, but quite a different ethical beast when what you're editing is intended to, or has, self-awareness.[/QUOTE] Yea, Because you give me a story (again published when gene edited was privately from main public and give limited supported by government) from a less known furry site. Should just give me a more updated realistic example to against of now create an animal-like human (human-like animal) hybrid and it's flaws.

[QUOTE=ChadMcGoatMan;52283909]Yea, Because you give me story (again published when gene edited was privated from main public and give limited supported by government) from less know furry site. Should just give me more updated realistic example to against of now create animal-like human (human-like animal) hybird.[/QUOTE]It's not meant to serve any other purpose than to make one think about the consequences of experimentation on sentient beings. Believing that current gene manipulation tech is perfect enough for creating new sentient species on the first try like it's just some character creator in an RPG is honestly absurd. Not to mention if we had the tech to make this sort of thing possible, we'd be seeing it used on humans first for e.g. congenital disorders that evade current solutions long before ever seeing the idea of creating new sapient species suggested. [editline]edit[/editline] Let's look at what's talked about in the article. A cheap kit that allows one to do things like make bacteria produce insulin, or make spicy tomatos, fairly simply. Existing genes inserted into simple, existing species, experiments that have been done before and proven working. Compare that to the difficulty of making a bipedal fox with human intelligence. It's not merely a matter of inserting the fur gene, the pointy ears gene and the muzzle gene into a person.

[QUOTE=Sgt Doom;52283914] Let's look at what's talked about in the article. A cheap kit that allows one to do things like make bacteria produce insulin or make spicy tomatos, fairly simply. Existing genes inserted into simple, existing species, experiments that have been done before and proven working. Compare that to the difficulty of making a bipedal fox with human intelligence. It's not merely a matter of inserting the fur gene, the pointy ears gene and the muzzle gene into a person.[/QUOTE] Well this in my mind the late stages of complete first generation of gene editing. And because of its limited version that government proved for public to practice bioengineering and genetic engineering. [QUOTE=Sgt Doom;52283914]It's not meant to serve any other purpose than to make one think about the consequences of experimentation on sentient beings. Believing that current gene manipulation tech is perfect enough for creating new sentient species on the first try like it's just some character creator in an RPG is honestly absurd. Not to mention if we had the tech to make this sort of thing possible, we'd be seeing it used on humans first for e.g. congenital disorders that evade current solutions long before ever seeing the idea of creating new sapient species suggested.[/QUOTE] Well that's soft eugenics and sapient rights that I glad you point about. And I have no problem about that.

i kind of think that only vetted institutions should have access to genetic manipulation technologies. like, look at this [quote]At Acera, an elementary and middle school in Massachusetts, 13-year-old Abby Pierce recently completed a CRISPR experiment, genetically modifying bacteria so that it could grow in an antibiotic that would have killed it otherwise.[/quote] if a 13 year old can create an antibiotic resistant strain of bacteria, someone else with some more effort could create a potent bioweapon. hell, someone could accidentally create some terrible disease and cause a pandemic if there isn't some sort of oversight

[QUOTE=Ninja Gnome;52283944]i kind of think that only vetted institutions should have access to genetic manipulation technologies. like, look at this if a 13 year old can create an antibiotic resistant strain of bacteria, someone else with some more effort could create a potent bioweapon. hell, someone could accidentally create some terrible disease and cause a pandemic if there isn't some sort of oversight[/QUOTE] Otherwords Bioengineered Zombie/Mutantic Apocalypse.

[QUOTE=Ninja Gnome;52283944]i kind of think that only vetted institutions should have access to genetic manipulation technologies. like, look at this if a 13 year old can create an antibiotic resistant strain of bacteria, someone else with some more effort could create a potent bioweapon. hell, someone could accidentally create some terrible disease and cause a pandemic if there isn't some sort of oversight[/QUOTE]Creating antibiotic resistant bacteria in an academic setting is as common as apple pie. They do it in colleges and more affluent high schools with nothing but plasmids and shocking the [I]E. coli[/I] into becoming competent for a few hours and begin taking up plasmids containing genes for fluorescence and ampicillin resistance. Even went and did it as a required project for Microbio lab in my second year. [URL]http://www.apsnet.org/EDCENTER/K-12/TEACHERSGUIDE/PLANTBIOTECHNOLOGY/Pages/Activity4.aspx[/URL] You're being unnecessary alarmist over something extremely common and safe.

[QUOTE=ExplodingGuy;52283968]Creating antibiotic resistant bacteria in an academic setting is as common as apple pie. They do it in colleges and more affluent high schools with nothing but plasmids and shocking the [I]E. coli[/I] into becoming competent for a few hours and begin taking up plasmids containing genes for fluorescence and ampicillin resistance. Even went and did it as a required project from Microbio lab in my second year. [URL]http://www.apsnet.org/EDCENTER/K-12/TEACHERSGUIDE/PLANTBIOTECHNOLOGY/Pages/Activity4.aspx[/URL] You're being unnecessary alarmist over something extremely common and safe.[/QUOTE] perhaps resistant bacteria is not as much of an issue, but the idea of people having the tools to easily genetically engineer in their garage is somewhat terrifying to me. if the tools are available and able to be acquired easily, there will be people who will want to make weapons from it. a correctly engineered virus or bacteria has the potential to cause more loss of human life than any bomb. someone infects themself with something nasty they've concocted in their home bio lab and hops on an international flight you've potentially infected dozens who will take that disease to their respective countries and spread it from there.

[QUOTE=Ninja Gnome;52283986]perhaps resistant bacteria is not as much of an issue, but the idea of people having the tools to easily genetically engineer in their garage is somewhat terrifying to me. if the tools are available and able to be acquired easily, there will be people who will want to make weapons from it. a correctly engineered virus or bacteria has the potential to cause more loss of human life than any bomb. someone infects themself with something nasty they've concocted in their home bio lab and hops on an international flight you've potentially infected dozens who will take that disease to their respective countries and spread it from there.[/QUOTE] Not sure why people are rating this dumb... I see huge risk in someone taking a strain of say... Ebola or Plague and making it more aggressive & Airborne. How can such a consideration, a -reasonable- thought be rated dumb?

[QUOTE=nuttyboffin;52284165]Not sure why people are rating this dumb... I see huge risk in someone taking a strain of say... Ebola or Plague and making it more aggressive & Airborne. How can such a consideration, a -reasonable- thought be rated dumb?[/QUOTE] But science tho Fuck caution /s

[QUOTE=Sgt Doom;52283914]It's not meant to serve any other purpose than to make one think about the consequences of experimentation on sentient beings. Believing that current gene manipulation tech is perfect enough for creating new sentient species on the first try like it's just some character creator in an RPG is honestly absurd. Not to mention if we had the tech to make this sort of thing possible, we'd be seeing it used on humans first for e.g. congenital disorders that evade current solutions long before ever seeing the idea of creating new sapient species suggested. [editline]edit[/editline] Let's look at what's talked about in the article. A cheap kit that allows one to do things like make bacteria produce insulin, or make spicy tomatos, fairly simply. Existing genes inserted into simple, existing species, experiments that have been done before and proven working. Compare that to the difficulty of making a bipedal fox with human intelligence. It's not merely a matter of inserting the fur gene, the pointy ears gene and the muzzle gene into a person.[/QUOTE] You can't make an omelette without breaking a few eggs. There's going to be errors, there's going to be failed experiments. That's a fact of science, and if you're not willing to take the risk in the name of advancing humanity's collective knowledge [i]find another field to work in[/i]. There will be people willing to volunteer for whatever crazy shit they come up with, and that includes effectively what is FEV. Is it difficult? Sure. Will there be failures? Sure. Would I sign up for it? .....probably the second or third round, actually, if it paid well enough. If they can manage to change the genome of an already made person to look like they evolved from vulpines or felines instead of the path we already did, then they can use it to cure horrible genetic diseases, and I'd be more than happy to be a part of that. It may seem silly at first glance, but being able to get a shot and become a fursona means the technology necessary to push medical science 250 years into the future has arrived.

I'm alright with gene editing to help eliminate diseases or genetic conditions like ALS, multiple sclerosis, etc. but I'm worried about something like GATTACA happening. I don't want a world where there's two kinds of people. Those who have been genetically enhanced to become superhuman, and those who have not.

[QUOTE=TestECull;52284228]You can't make an omelette without breaking a few eggs. There's going to be errors, there's going to be failed experiments. That's a fact of science, and if you're not willing to take the risk in the name of advancing humanity's collective knowledge [i]find another field to work in[/i]. There will be people willing to volunteer for whatever crazy shit they come up with, and that includes effectively what is FEV. Is it difficult? Sure. Will there be failures? Sure. Would I sign up for it? .....probably the second or third round, actually, if it paid well enough. If they can manage to change the genome of an already made person to look like they evolved from vulpines or felines instead of the path we already did, then they can use it to cure horrible genetic diseases, and I'd be more than happy to be a part of that. It may seem silly at first glance, but being able to get a shot and become a fursona means the technology necessary to push medical science 250 years into the future has arrived.[/QUOTE] we shouldn't take the risks if the damage incurred by it going wrong exceeds the benefits of it going right - especially if failures cannot be localised to a particular time and space science is a tool built upon thousands of years of experience, it is not infallible and its dangerous to treat it as such

[QUOTE=GÃ©za!;52284187]But science tho Fuck caution /s[/QUOTE] Operation Darkwinter here we come!

[QUOTE=Ninja Gnome;52283944]i kind of think that only vetted institutions should have access to genetic manipulation technologies. like, look at this if a 13 year old can create an antibiotic resistant strain of bacteria, someone else with some more effort could create a potent bioweapon. hell, someone could accidentally create some terrible disease and cause a pandemic if there isn't some sort of oversight[/QUOTE] There are bioethical issues related to synthetic biology about creating bio weapons. However, anti-biotic resistance isn't the best case to present when arguing that. Ampicilin resistant bacteria (that's only one of many various types) are commonly grown on plates in genetic experimentation simply because it allows one to restrict the bacterial growth on the plate to only the experimental colonies. It's a common method, not dangerous, and one of the only methods of performing experiments with bacteria at all. If you want examples of potential future issues in sythetic biology, this is a better case to read up on (being able to purchase segments of various known genomes in parts may have unintended consequences) [URL="http://scienceblogs.com/scientificactivist/2006/06/14/the-guardian-is-able-to-purcha/"]http://scienceblogs.com/scientificactivist/2006/06/14/the-guardian-is-able-to-purcha/[/URL]

Did I miss something? Why are all the comments on a middle school getting new science equipment furry related.

[QUOTE=laserpanda;52284585]Did I miss something? Why are all the comments on a middle school getting new science equipment furry related.[/QUOTE] OP divulged into one of his deepest fantasies, then deleted it from OP.

[QUOTE=pentium;52284608]OP divulged into one of his deepest fantasies, then deleted it from OP.[/QUOTE] luckily someone was fast enough to quote it i knew a guy once who invited me to contribute to his 'biohacking' project to make an open-source machine that makes real furries. last i checked he was lying to investors about what the project was about to get funds. [url=https://vulpinedesigns.co.uk/]here's his website[/url] also, [url=http://dsdfox.deviantart.com/art/An-Atom-Of-Freedom-306516880]he has a book[/url] (warning: it's horrible)

[QUOTE=laserpanda;52284585]Did I miss something? Why are all the comments on a middle school getting new science equipment furry related.[/QUOTE] They take joke just to literal and acting emotionally triggered as result it put a disclaimer (and later deleted altogether due of this happen again, I think they easily trigger again).

[QUOTE=ChadMcGoatMan;52284715]They take joke to literal and acting emotionally triggered as result it put a disclaimer (and later deleted altogether due of this again, I think they easily trigger again).[/QUOTE] Just because you are still technically new here (technically by six months, but whatever), FYI half of facepunch hate furries and the other 25% are in the closet. Furry comments still rile the shit out of them. The other 25% don't give a fuck.

[QUOTE=ChadMcGoatMan;52284715]They take joke to literal and acting emotionally triggered as result it put a disclaimer (and later deleted altogether due of this happen again, I think they easily trigger again).[/QUOTE] What? Responding to a dumb comment is being triggered now?

I can't wait to see the "My Little Abomination" biology kit at Toys-r-Us.

[QUOTE=pentium;52284741]Just because you are still technically new here (technically by six months, but whatever), FYI half of facepunch hate furries and the other 25% are in the closet. Furry comments still rile the shit out of them. The other 25% don't give a fuck.[/QUOTE] I think you'll find a lot of people here don't necessarily hate furries, but do hate it when they put it all up on display. Keep that in your own room basically. Like Chad here was perfectly fine, it's just in this thread he went full fursona and tried to argue for creating fucked up hybrids of animals and humans which is just fucked.

I'm not that worried about these sorts of kits being used to create new antibiotic-resistant strains unknown to science. The thing wouldn't be $150 if it had more than essentially Lego-capability for a select few well-studied genomes for a well-studied species of bacteria. [QUOTE=TornadoAP;52284912]I think you'll find a lot of people here don't necessarily hate furries, but do hate it when they put it all up on display. Keep that in your own room basically. Like Chad here was perfectly fine, it's just in this thread he went full fursona and tried to argue for creating fucked up hybrids of animals and humans which is just fucked.[/QUOTE]It's an interesting ethical dilemma to discuss, I find. [QUOTE=TestECull;52284228]You can't make an omelette without breaking a few eggs. There's going to be errors, there's going to be failed experiments. That's a fact of science, and if you're not willing to take the risk in the name of advancing humanity's collective knowledge [i]find another field to work in[/i]. There will be people willing to volunteer for whatever crazy shit they come up with, and that includes effectively what is FEV. Is it difficult? Sure. Will there be failures? Sure. Would I sign up for it? .....probably the second or third round, actually, if it paid well enough. If they can manage to change the genome of an already made person to look like they evolved from vulpines or felines instead of the path we already did, then they can use it to cure horrible genetic diseases, and I'd be more than happy to be a part of that. It may seem silly at first glance, but being able to get a shot and become a fursona means the technology necessary to push medical science 250 years into the future has arrived.[/QUOTE]If some loony willingly wants to sign up for mutation, that doesn't bother me as much. The first generation of any sort of furry project isn't going to be altering existing individuals, though, since that's a lot harder; it'll be altered embryos who'll be born into an experiment they did not consent to, likely will suffer greatly during their short existence, and cursed with self-awareness to contemplate it.

I can be considered a furry and I can't give a shit about "creating furries" because that gonna be gross and weird. The entire point of the deal to me is escape from reality, tainting the escapism with some gross probably largely malformed experiments would be horrible. Better make me live forever, immune to cancer, with indestructible liver. Maybe cure my fucking asthma, or at least some allergies. Tails come on buttplugs, no need to reinvent the wheel. [editline]29th May 2017[/editline] Also if you wanna see a scary outlook for our gene-modding future, read Peter Watts' Echopraxia. He's different from most scify schlock by putting an uncanny amount of scientific rigour to his depressive ideas of the future, which makes them all the scarier (last few pages of the book is literally him citing sources and elaborating on how exactly realistic this or that concept is (and most of them are "quite realistic"))

[QUOTE=millan;52285629] Also if you wanna see a scary outlook for our gene-modding future, read Peter Watts' Echopraxia. He's different from most scify schlock by putting an uncanny amount of scientific rigour to his depressive ideas of the future, which makes them all the scarier (last few pages of the book is literally him citing sources and elaborating on how exactly realistic this or that concept is (and most of them are "quite realistic"))[/QUOTE] So the author is really trying it's best to being main Biopunk theme into Hard Science fiction. Ok and kinda succeed doing it's best.

[QUOTE=millan;52285629]I can be considered a furry and I can't give a shit about "creating furries" because that gonna be gross and weird. The entire point of the deal to me is escape from reality, tainting the escapism with some gross probably largely malformed experiments would be horrible. Better make me live forever, immune to cancer, with indestructible liver. Maybe cure my fucking asthma, or at least some allergies. Tails come on buttplugs, no need to reinvent the wheel. [editline]29th May 2017[/editline] Also if you wanna see a scary outlook for our gene-modding future, read Peter Watts' Echopraxia. He's different from most scify schlock by putting an uncanny amount of scientific rigour to his depressive ideas of the future, which makes them all the scarier (last few pages of the book is literally him citing sources and elaborating on how exactly realistic this or that concept is (and most of them are "quite realistic"))[/QUOTE] At the same time I wouldn't mind deep dive VR that would allow me to experience furry stuff in a way that has less chance of being horrific. Genetically engineering a being just to be in a sexual relationship with it is absolutely fucked, and for modifying yourself, genetic engineering / body modding would take decades of uncanny valley horror before we'd create furries that were even visually acceptable. It's not impossible for an anthro animal to be visually appealing irl, I've seen some realistic fursuits that look pretty nice, but the transition period would be so horrifying that it'd probably turn everyone off from the idea. The future for furries is in VR, in my opinion. Wait for technology to catch up.