• The Lsd, no effect on me?
    56 replies, posted
[QUOTE=macerator;21111170] Yeah, my google fu says that it bypasses the GI tract, so it kicks in faster, but with LSD the doses are so small, and the onset timing is so long that i personally think that its a placebo effect. (also, it diffuses into the blood stream, and goes to your egg salad faster, nothing to do with availability.)[/QUOTE] Whilst I agree with the rest of your post. I don't understand why you draw this conclusion. Your evidence seems to suggest sublingual ROA makes it onset quicker, yet you draw the opposite conclusion? Sublingual application will get it into your blood faster therefore making it kick in faster, it seems like a no brainer to me.
Higher bio-availability doesn't means faster onset. Also, I think LSD's many routes have 100% bio-availability. Oral and sub lingual for example.
Actually, higher bioavailablity almost ALWAYS means faster onset due to the fact that the effects become noticable earlier. Name a drug where higher bioavailablity doesn't equal faster onset? For example, with Mephedrone, bioavailablity (in order of most bio available to least is): Injection, Plugging, Insufflation, Oral. You'll find rate of onset corresponds.
[QUOTE=kobilica;21119727]Higher bio-availability doesn't means faster onset. Also, I think LSD's many routes have 100% bio-availability. Oral and sub lingual for example.[/QUOTE] the only thing that has 100% ba is intravenous injection, by definition.
[QUOTE=Pome;21121631]the only thing that has 100% ba is intravenous injection, by definition.[/QUOTE] Indeed, and even then BA of IV is normally 99.9% just because our circulatory system is not 100% efficient.
It seems to me that if you consciously wait for the effects of LSD to start, that will lengthen the on set period. The amount of time that it takes, in my opinion is around the difference in onset times from oral and sublignual. In other words, if you're waiting for your trip to start, the amount of time for it to happen is long enough that it wouldn't matter how you took it, orally, or under the tongue. Also, because of the difficulty of making LSD, losing the 2 biggest makers WOULD and DID and DOES have an effect on the purity and availability of LSD. Its not like bud that any idiot can grow, even with meth or crack, any idiot with a stove can make it. LSD is probably harder to make than heroin from raw poppies.
You can't make meth with a stove, you need pseudoephedrine for a start, which is difficult to get in most places. You also need phosphate and potassium or some shit. Not things that you find laying around the house, that's for sure. It's also pretty hazardous to cook meth, makes toxic gases and can explode as well.
[QUOTE=Dan The Man;21123251]You can't make meth with a stove, you need pseudoephedrine for a start, which is difficult to get in most places. You also need phosphate and potassium or some shit. Not things that you find laying around the house, that's for sure. It's also pretty hazardous to cook meth, makes toxic gases and can explode as well.[/QUOTE] indeed. red phosphate, it is.
[QUOTE=macerator;21123079] Also, because of the difficulty of making LSD, losing the 2 biggest makers WOULD and DID and DOES have an effect on the purity and availability of LSD. Its not like bud that any idiot can grow, even with meth or crack, any idiot with a stove can make it. LSD is probably harder to make than heroin from raw poppies.[/QUOTE] If there's a demand, someone will fill it. it's hard to make LSD but because of how small doses are it's profitable. I'm sure there's still people out there who are making it.
[QUOTE=Pome;21123657]indeed. red phosphate, it is.[/QUOTE] red phosphorus bbz not phosphate
thanks bb.
stop watching breaking bad pome. [editline]03:05AM[/editline] :smug:
[quote=macerator;21068253]the shit that your dealer gets are some sort of research chemicals. They may get you high, but they aren't lsd. Lsd is balls hard to make, in part because its a fragile molecule. Plus the fact that the market doesn't have its 2 biggest makers got taken down a few years back. Also, as far as taking it or leaving it on your tongue, its all placebo.[/quote] hey everyone look at me i can spout bullshit out of my asshole
read the follow up post that I cited, please. [editline]12:17AM[/editline] [QUOTE=Luke510;21124318]If there's a demand, someone will fill it. it's hard to make LSD but because of how small doses are it's profitable. I'm sure there's still people out there who are making it.[/QUOTE] Of course there are, but these guys made it by the 10's of kilograms. They got busted with around 13 million hits if i do believe so. They sold it around the United States and Europe. Its the scale at which they made it at.
The first time I took acid I took 3 tabs, let them all sit on my tongue for about 10 minutes then swallowed them as I was instructed. I waited for about an hour before I could tell I was high. The next time I took acid, i left them under my tongue (4 tabs) for about 15 minutes then swallowed them. I then proceeded to start packing a bowl and actually forgot I had taken acid and the effects kicked in alot faster, I think. Probably somewhere around 5-10 minutes after I swallowed them. I don't know if it's because I left them under my tongue or if I forgot about it. That's what I do every time now. Leave them under my tongue, swallow, move on to something else and forget about the acid. Then all of a sudden you feel your mind warp and you get sucked into a world where everything shape shifts and is hilariously funny. Then when you listen to music things that shouldn't be talking to you (comics, action figures, cups) ARE talking to you and you can see your fucking music. @OP Either you got a fake batch or you need to take more. Even if it took an hour, the effects last (for me) around 8-10 hours without eating and 6-8 hours with eating. it's definitely something you need to reserve time for.
[QUOTE=Dan The Man;21120532]Actually, higher bioavailablity almost ALWAYS means faster onset due to the fact that the effects become noticable earlier. Name a drug where higher bioavailablity doesn't equal faster onset? For example, with Mephedrone, bioavailablity (in order of most bio available to least is): Injection, Plugging, Insufflation, Oral. You'll find rate of onset corresponds.[/QUOTE] That is true, but it's not same other way around. If you get faster onset "that" route, it doesn't means "that" route has any different bioavailability than other route. For example, xanax snorted has same bio-availability that oral, yet it comes up faster. Just because nose absorbs drug faster than stomach, it doesn't means it has higher bio-availability.
[QUOTE=macerator;21134291]read the follow up post that I cited, please. [editline]12:17AM[/editline] Of course there are, but these guys made it by the 10's of kilograms. They got busted with around 13 million hits if i do believe so. They sold it around the United States and Europe. Its the scale at which they made it at.[/QUOTE] at a hit being ~100ug, 13 million hits would use 1.3kilograms.
[QUOTE=kobilica;21137926]That is true, but it's not same other way around. If you get faster onset "that" route, it doesn't means "that" route has any different bioavailability than other route. For example, xanax snorted has same bio-availability that oral, yet it comes up faster. Just because nose absorbs drug faster than stomach, it doesn't means it has higher bio-availability.[/QUOTE] lol, Xanax is not lipophilic. You can't get any effects insufflated... All effects from Xanax insufflated are due to the drip so it's just oral dosing by proxy... RE: RC's, RCs would still give you effects and the only ones that'd be put in place of LSD are BromoDragonFLY, DOx and PERHAPS a 2C-X but their effect profiles are different and they'd get you high still so it's a moot point.
[QUOTE=Dan The Man;21139368]lol, Xanax is not lipophilic. You can't get any effects insufflated... All effects from Xanax insufflated are due to the drip so it's just oral dosing by proxy... RE: RC's, RCs would still give you effects and the only ones that'd be put in place of LSD are BromoDragonFLY, DOx and PERHAPS a 2C-X but their effect profiles are different and they'd get you high still so it's a moot point.[/QUOTE] Apparently, reported by people, Xanax does have effect, but at same time, people said it's waste :D Anyway, I still think faster onset doesn't means higher bioavailability. What about weed :P, when you cook it right, the same amount orally gets you into same place than same amount smoked.
[QUOTE=kobilica;21141125] What about weed :P, when you cook it right, the same amount orally gets you into same place than same amount smoked.[/QUOTE] You sure about that? "Bioavailability of THC when inhaled is 20% versus 6% when ingested" [url]http://www.cannabisculture.com/backissues/cc08/oppression/fallacy.html[/url]
[QUOTE=Dan The Man;21139368] RE: RC's, RCs would still give you effects and the only ones that'd be put in place of LSD are BromoDragonFLY, DOx and PERHAPS a 2C-X but their effect profiles are different and they'd get you high still so it's a moot point.[/QUOTE] Sorry, but when I buy shit, I hope to get what I ask (or pay) for. Research chemicals can fuck you up pretty hard, for example Dragon fly can last up to a week. Its the same thing as ecstasy. Sure you might be getting heroin or meth or caffine, but they all get you just as high as MDMA does, so whats the problem? (this is why I like molly)
[QUOTE=Dan The Man;21141218]You sure about that? "Bioavailability of THC when inhaled is 20% versus 6% when ingested" [url]http://www.cannabisculture.com/backissues/cc08/oppression/fallacy.html[/url][/QUOTE] I think it's quite more than 6%. Maybe that 6% is when you eat unprocessed cannabis. Or, you are probably right. Maybe because I have seen people get more fucked up on cookies than smoking it hehe.
You get more when you eat it would be why. 20% of a gram v. 6% of a quarter (or however much your friends use) NOTE i didn't actually do any math, but hopefully you get the point.
[QUOTE=macerator;21155502]You get more when you eat it would be why. 20% of a gram v. 6% of a quarter (or however much your friends use) NOTE i didn't actually do any math, but hopefully you get the point.[/QUOTE] Yeah, I get it. It's just strange, how the heck just 6% of it it's absorbed.
[QUOTE=macerator;21141520]Sorry, but when I buy shit, I hope to get what I ask (or pay) for. Research chemicals can fuck you up pretty hard, for example Dragon fly can last up to a week. Its the same thing as ecstasy. Sure you might be getting heroin or meth or caffine, but they all get you just as high as MDMA does, so whats the problem? (this is why I like molly)[/QUOTE] Yea pretty much. I remember I had this one dude who always told me how the pills were, and I remember he told me one was trippy and people thought it was laced with acid. it's better if you have a warning instead of thinking its e and going somewhere and just start tripping out. white motos was the pill.
[QUOTE=macerator;21141520]Sorry, but when I buy shit, I hope to get what I ask (or pay) for. Research chemicals can fuck you up pretty hard, for example Dragon fly can last up to a week. Its the same thing as ecstasy. Sure you might be getting heroin or meth or caffine, but they all get you just as high as MDMA does, so whats the problem? (this is why I like molly)[/QUOTE] You're expecting a dealer to be conscientious? Be realistic. DragonFLY doesn't last up to a week, it lasts about 24 hours for most people. Both DOx and BMDFLY are very dangerous and LSD is not. It's something to worry about when buying LSD but DOx and BMDFLY are quite rare.
[QUOTE=Pome;21011824]you kept the tab on your tongue for 45 minutes? damn, that's perseverance.[/QUOTE] That's what I do everytime. Or I slip it under my tongue.
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