You'd think that someone with such big muscles could slice butter like 'a knife through butter'..
[QUOTE=Hiurst;34006743]The title does not say the same thing as the article says.
'hurt brain' implies something way more serious and different than what the article says. You are legit dumb if you can't see that!!![/QUOTE]
[i]Somebody's[/i] on a high-fat diet.
Are the injuries permanent or do you just have to stop eating like a fat bastard for a while?
I think it may be temporary but if you continue doing it could cause permanent damage. I never really eat much anyway.
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[highlight](User was banned for this post ("image macro" - Swebonny))[/highlight]
[QUOTE=Extroll;34024703]Are the injuries permanent or do you just have to stop eating like a fat bastard for a while?[/QUOTE]
Pretty sure brain damage is permanent.
[QUOTE=Chinook249;34026705][IMG]http://d37nnnqwv9amwr.cloudfront.net/entries/icons/original/000/007/666/_57c8a1a431a592af806925e57258202f.png[/IMG][/QUOTE]
I don't think high-fat diets damaging the hypothalamus is very obvious...
I wonder if the guy in the video was using margarine or real butter, if it's the latter I think I could manage two of those sandwiches (it would be even worse for my health though, I imagine.
BTW dietary fat =/= body fat.
[QUOTE=SCopE5000;34031359]BTW dietary fat =/= body fat.[/QUOTE]
even then, studies have shown that higher body fat = worse memory
like, just body fat. nothing else. body fat. no hypertention, heart disease, anything. just high body fat.
So is that why a really fat man decides to live on the north pole, once a year going to every child on the planet and giving them a random present, or coal if he thinks they've been bad?
[QUOTE=willer;34035379]So is that why a really fat man decides to live on the north pole, once a year going to every child on the planet and giving them a random present, or coal if he thinks they've been bad?[/QUOTE]Santa is hardly "really fat"
[QUOTE=valkery;34006729]This guy does have a screen name you know.... :smith:[/QUOTE]
its obvious he cant read
I don't think this study's very reliable. All the sources I can find that mention this study don't mention what the rodents are being fed, only that it's "high fat", not even mentioning how much fat they're getting in comparison to what they normally are supposed to eat. They could have been fed a pile of lard and nothing more for all we know.
It's a fucking rat model study.
This means literally nothing unless it's replicated in humans (who have been surviving off high fat food since the times we used to run like blubbering bitches from massive prehistoric cats).
Consuming a shitload of garlic makes rats double their testosterone. In humans, consuming an equivalent amount of garlic would just make you stink.
[QUOTE=JaegerMonster;34042747]It's a fucking rat model study.
This means literally nothing unless it's replicated in humans (who have been surviving off high fat food since the times we used to run like blubbering bitches from massive prehistoric cats).
Consuming a shitload of garlic makes rats double their testosterone. In humans, consuming an equivalent amount of garlic would just make you stink.[/QUOTE]
oh god are you serious
[QUOTE=GamerKiwi;34041780]I don't think this study's very reliable. All the sources I can find that mention this study don't mention what the rodents are being fed, only that it's "high fat", not even mentioning how much fat they're getting in comparison to what they normally are supposed to eat. They could have been fed a pile of lard and nothing more for all we know.[/QUOTE]
This. Not every study should be taken at it's face value.
Yes, I know this may be hard to believe, but there are such things as shitty studies!!!
We have no indication of their feed, other than it was high in fat. What types of fat, better yet, what other macronutrients were they fed, if any?
[QUOTE=AceOfDivine;34035409]Santa is hardly "really fat"[/QUOTE]
The American Santa Claus is really fat.
oh btw
"Researchers from the University of Washington School of Medicine looked at the brains of [B]rodents that were bred to become obese[/B] and found that when placed on a high-fat diet"
So... basically this study is even less relative than I initially thought.
Basically what we have here is a study that is showing obese mice have similar hypothalamus inflammation to... obese people.
"study does not show whether the "hypothalamus caused obesity, or if the obesity caused the changes in the hypothalamus." The findings show only a correlation."
Not a very good study to take and run with "high fat diets induce brain damage people!!!".
[QUOTE=JaegerMonster;34042774]This. Not every study should be taken at it's face value.
Yes, I know this may be hard to believe, but there are such things as shitty studies!!!
We have no indication of their feed, other than it was high in fat. What types of fat, better yet, what other macronutrients were they fed, if any?[/QUOTE]
Yeah, you can't really take much from animal studies in that regard
[QUOTE=JaegerMonster;34042945]oh btw
"Researchers from the University of Washington School of Medicine looked at the brains of [B]rodents that were bred to become obese[/B] and found that when placed on a high-fat diet"
So... basically this study is even less relative than I initially thought.
Basically what we have here is a study that is showing obese mice have similar hypothalamus inflammation to... obese people.
"study does not show whether the "hypothalamus caused obesity, or if the obesity caused the changes in the hypothalamus." The findings show only a correlation."
Not a very good study to take and run with "high fat diets induce brain damage people!!!".[/QUOTE]
There have been studies before this one that [url=http://content.karger.com/produktedb/produkte.asp?typ=pdf&file=000153423]seemed to suggest the same thing[/url]
[release]Dysfunction of specific hypothalamic neurons is regarded as an important mechanism predisposing to the development of obesity. [b]Recent studies have revealed that the consumption of fat-rich foods can activate an inflammatory response in the hypothalamus[/b], which disturbs the anorexigenic and thermogenic signals generated by the hormones leptin and insulin, leading in turn to anomalous body mass control. Depending on diet composition, cytokines are expressed in the hypothalamus, contributing to the activation of intracellular inflammatory signal transduction. At least 4 distinct signaling pathways have been identified and the molecular mechanisms leading to the impairment of the leptin and insulin actions have been determined. Here, we present the mechanisms involved in diet-induced resistance to leptin and insulin action in the hypothalamus and discuss some of the potential applications of this knowledge in the therapeutics of obesity.[/release]
[QUOTE=Zeke129;34044408]There have been studies before this one that [url=http://content.karger.com/produktedb/produkte.asp?typ=pdf&file=000153423]seemed to suggest the same thing[/url]
[release]Dysfunction of specific hypothalamic neurons is regarded as an important mechanism predisposing to the development of obesity. [b]Recent studies have revealed that the consumption of fat-rich foods can activate an inflammatory response in the hypothalamus[/b], which disturbs the anorexigenic and thermogenic signals generated by the hormones leptin and insulin, leading in turn to anomalous body mass control. Depending on diet composition, cytokines are expressed in the hypothalamus, contributing to the activation of intracellular inflammatory signal transduction. At least 4 distinct signaling pathways have been identified and the molecular mechanisms leading to the impairment of the leptin and insulin actions have been determined. Here, we present the mechanisms involved in diet-induced resistance to leptin and insulin action in the hypothalamus and discuss some of the potential applications of this knowledge in the therapeutics of obesity.[/release][/QUOTE]
Sorry but without having access to the references or full text, there's no way any relevant information can be gleaned off this.
Again, if the references are all rat model studies, especially knockout types, it doesn't hold much ground. At this point the only strong connection is that obese people have inflammation in the hypothalamus.
There are other factors at play too. Was it just a high fat diet? High fat, no protein? High fat, no carbohydrates? high fat, high carbohydrates?
[QUOTE=JaegerMonster;34044933]Sorry but without having access to the references or full text, there's no way any relevant information can be gleaned off this.
Again, if the references are all rat model studies, especially knockout types, it doesn't hold much ground. At this point the only strong connection is that obese people have inflammation in the hypothalamus.
There are other factors at play too. Was it just a high fat diet? High fat, no protein? High fat, no carbohydrates? high fat, high carbohydrates?[/QUOTE]
The full text is just a literature review, so you'd be able to get the sources out of the citation list