Nicotine vaccine prevents nicotine from reaching the brain - Polidicks

ITT people have no idea how addictions work.

[QUOTE=Jurikuer;35804712]Okay well what about the nicotine that our brains naturally produce? Does it inhibit that too, because that sounds counter-productive. Cure an addiction by shutting down a natural process in the brain. Here's a solid way to quit smoking. STOP SMOKING. People make it out to be the hardest thing in the world. Well something those people don't seem to understand, no matter how you word it or how many times you say it, the only thing that makes it hard is the fact that you make it seem so hard. Some people need help, I get that. It's not easy to quit. But to treat it as some kind of disease by making a vaccine for it is a little much I think.[/QUOTE] Wrong. Nicotine will change the proportion of receptors in the reward centre of the brain meaning that the body depends on an external dose to maintain normal levels of brain activity (in that area). People with physical addictions have a disease which is no less real than hypertension or diabetes. In regards to the endogenous ligand (acetylcholine), that isn't supposed to leave synaptic clefts anyways due to acetylcholinesterases that break it down quick smart.

And then nanomachines conquered the world

It's bought out by big Tobacco and we never hear of it ever again.

[QUOTE=areolop;35804024]Do you..- what. Nicotine is the thing that keeps people addicted to tobacco. This 'vaccine' will rid smokers (if chosen) of their addiction to tobacco.[/QUOTE] nicotine is addictive, but there's about 8 other chemicals in tobacco which synergise with the nicotine and make it a pretty potent maoi.

This might be nice for those people who want to try out smoking/like the taste but don't want to get addicted to it.

champix works well. however, half the addiction is actually the action of taking time out of your day to sit down and smoke. that's the hardest bit to beat and this vaccine won't help shit. [editline]3rd May 2012[/editline] [QUOTE=Orkel;35806850]This might be nice for those people who want to try out smoking/like the taste but don't want to get addicted to it.[/QUOTE] .... right

[QUOTE=Averice;35805616]The government does it this way to make you think they care about your health, they probably laugh while rolling in the cash smokers give to the government each year. I agree it does prevent some people, but if everyone suddenly gave up smoking they'd be all "oh fuck."[/QUOTE] In countries where there is free healthcare the cost of treating smokers is higher than what they make off of the taxes

[QUOTE=Orkel;35806850]This might be nice for those people who want to try out smoking/like the taste but don't want to get addicted to it.[/QUOTE] I'm not sure there'd be any reason to smoke if you didn't get the nicotine hit.

I'm a everyday user of snus, and I think snus should be made legal in more countries than just Sweden, Norway and Denmark (Not sure about Finland). At least as a aid against smoking. EU is against it, they're thinking it will cause mouth cancer, but look at Swedish statistics they have the lowest tobacco death toll in the world. Going from smoking to snus reduces the death toll from tobacco a lot. Smokers who go to snus says it's a lot easier and it is much healthier than smoking. Taking this vaccine would probably give a minor number of people narcolepsy or other bad side effects. Imagine people who can't quit even after taking this vaccine, instead of smoking one cigarette at a time they would go with three to override the function of the vaccine, just to feel better. Nicotine itself isn't really any danger in normal dosages like in tobacco. And the danger is just all the additives especially in cigarettes. The vaccine against nicotine is pointless, as it won't remove the cravings, it could work for a lot of people determined to quit nicotine. But as it is override able they could just smoke a lot more which also would be more dangerous in the end. And won't this be fairly exhausting for the immune system if they kept using nicotine? This is some dangerous shit in the wrong hands, they could probably make it against vital substances.

[QUOTE=Jurikuer;35804712]Okay well what about the nicotine that our brains naturally produce? Does it inhibit that too, because that sounds counter-productive. Cure an addiction by shutting down a natural process in the brain. Here's a solid way to quit smoking. STOP SMOKING. People make it out to be the hardest thing in the world. Well something those people don't seem to understand, no matter how you word it or how many times you say it, the only thing that makes it hard is the fact that you make it seem so hard. Some people need help, I get that. It's not easy to quit. But to treat it as some kind of disease by making a vaccine for it is a little much I think.[/QUOTE] I'm sorry, but I have to disagree. I've seen people try to quit, hell my mother is one of them. She succeeded at one point in time, but she went back some years later. Then she tried again, and it damn near tore our family apart from the stress it was causing. This vaccine would help, but it wasn't the addiction itself she was having an issue with, it was the stress that detoxing was causing.

[QUOTE=Chicken_Chaser;35804004]Nicotine ain't even addicting alone really but I guess what works works.[/QUOTE] Nicotine is suggested to be the most addictive substance on Earth, you probably wouldn't know if you(thankfully)haven't tried it.

Eh, I'm not having needles in my arm to stop my smoking habit. There's natural plant and herbal extracts that I've been using and I went from a pack a day to 1-2 cigarettes in the matter one 1 night. In fact I smoked my last one yesterday and I have no desire to buy a new pack. Quit in less than a week from natural methods. It's called Bell #35 if any of you are interested in quitting, you only need to pop 2-4 of those capsules a day and you're good to go.

[QUOTE=Jabberwocky;35807111]I'm not sure there'd be any reason to smoke if you didn't get the nicotine hit.[/QUOTE] Makes you look cool, daddy-o

Fantastic discovery, doubt the cigarette companies will like it though.

how will it stop smokers from smoking? I thought it just blocked the nicotine from reaching the brain so you smoke and smoke and smoke but you dont get your fix or something like that?

IIRC when you smoke the smoke is obviously inhaled into your lungs, from there the alveoli in your lungs transfer the nicotine to your circulatory system, where it basically pretends to be oxygen and binds with your red blood cells. So, is the nicotine being destroyed once it enters the blood stream or gets to the brain? If not, then where is it going?

[QUOTE=Chicken_Chaser;35804004]Nicotine ain't even addicting alone really but I guess what works works.[/QUOTE] Everyone rates him dumb but he's half right, there's plenty of evidence that without the (naturally occuring) MAOIs in tobacco, nicotine is far less addicting. ([URL]http://www.sciencedirect.com/science/article/pii/S0091305703002235[/URL] , [URL]http://www.jneurosci.org/content/25/38/8593.abstract[/URL])

Its tough to quit I gotta admit.. Right now I'm on week 2 with no cigarettes. I can feel my craving hitting the 3rd gear. But - mind over matter (even though some odd times I think its my mind that wants to smoke) No nicotine patches/gum for me either.. I just want to get rid of my addiction to nicotine even if I have to go through this craving stage.. (or withdrawal stage) It sucks when you are walking outside and all the people you notice are the ones who are smoking.

[QUOTE=Jurikuer;35804712]Okay well what about the nicotine that our brains naturally produce? Does it inhibit that too, because that sounds counter-productive. Cure an addiction by shutting down a natural process in the brain. Here's a solid way to quit smoking. STOP SMOKING. People make it out to be the hardest thing in the world. Well something those people don't seem to understand, no matter how you word it or how many times you say it, the only thing that makes it hard is the fact that you make it seem so hard. Some people need help, I get that. It's not easy to quit. But to treat it as some kind of disease by making a vaccine for it is a little much I think.[/QUOTE] you should start smoking man, it lets all those sticks up you ass loosen up THEN TRY TO QUIT

And then we can watch this vanish overnight. (Maybe because of Tobacco companies?)

[QUOTE=Jabberwocky;35807111]I'm not sure there'd be any reason to smoke if you didn't get the nicotine hit.[/QUOTE] It tastes nice and is pleasent to do sometimes imo

Will nicotine craving in humans eventually be treatable? Experts at Weill Cornell Medical College in New York have a nicotine vaccine that works to prevent it in mice. Humans may not be far behind. [QUOTE]The next step in the nicotine vaccine trials will be rats, then primates. If the vaccine is successful at preventing nicotine from reaching the brain in those animals, tests with human smokers will occur. Crystal stated that a successful run in human test subjects would pre-empt the habit in non-smokers and aid smokers in their cessation efforts.[/QUOTE] [URL="http://personalmoneynetwork.com/moneyblog/2012/07/02/nicotine-vaccine/"]Nicotine vaccine could cure addiction in humans[/URL] This is can be beneficial to those people who have COPD's and potential COPD's sufferers.

Earlier, this guy said [QUOTE=Stormcharger;35806891]In countries where there is free healthcare the cost of treating smokers is higher than what they make off of the taxes[/QUOTE] But I remember reading that it is cheaper for insurance companies (and governments I assume) to insure smokers because they will die before they have to treat them for expensive end of life disease (70+ years old). Is this right?