We May Have Reached The 'Apocalyptic Scenario' With Antibiotics - Polidicks

seems like we should probably fast-track development of all those smart approaches that pop up in the news every few months, by smart, i mean they still use the old anti-biotic but they deploy additional stuff like some form of enzyme or metal catalyst that dramatically weakens the bacteria before being hit by the anti-biotic [editline]8th December 2014[/editline] [QUOTE=FPSMango;46665387]People today aren't much worse at resisting common diseases today than they were before. Back in the day the flu would get you really sick and possible kill you, today it will just make you really sick. (unless you have some condition that weakens your immune system) Basically when we enter the post-antibiotic age we will not be more fucked than we were before antibiotics, we will just be fucked but still better off than we were before antibiotics. (Because we have other forms of modern medicine that they didn't have before that won't go away)[/QUOTE] what we have in a post-anti-biotic age: soap and showers what they didn't have in a pre-anti-biotic age: soap and showers

[QUOTE=J!NX;46665230]this was pre-removal they gave me different anti biotics and it stopped immediately[/QUOTE] Pretty certain that was you being allergic to the antibiotic. Not the antibiotic itself. Sounds like an allergic reaction to me, anyways. My mum had an allergic reaction to one of her insulin medications that resulted in eating making her nauseous. She lost something like 30 pounds on the month or two she was taking it, because she threw up virtually after every meal. It was terrible.

[QUOTE=Gmod4ever;46665434]Pretty certain that was you being allergic to the antibiotic. Not the antibiotic itself. Sounds like an allergic reaction to me, anyways. My mum had an allergic reaction to one of her insulin medications that resulted in eating making her nauseous. She lost something like 30 pounds on the month or two she was taking it, because she threw up virtually after every meal. It was terrible.[/QUOTE] I'm deathly allergic to penicillin / amoxicillin so probably

[QUOTE=paindoc;46665074]for one almost all antibiotics will cause some gut "difficulties" as the microflora and your gut biome is nuked. Antibiotics don't discriminate between mean nasty bacteria and the kind that help your digestion[/QUOTE] Yeah, my shits have been fucking haywire since I’ve started on a three month course of erothromycin.

[QUOTE=Ardosos;46664959]Don't most antibiotics make you really sick? Or am I thinking of some other kind of treatment?[/QUOTE] Pretty sure sepsis makes you sicker. :downs:

[QUOTE=PopLot;46665042][url=http://wh40k.lexicanum.com/wiki/Iron_Hands]THE FLESH IS WEAK[/url][/QUOTE] that's...different from what I was thinking... I was thinking "what if Ghost in the shell could come in our reality"?

[QUOTE=darkedone02;46665764]that's...different from what I was thinking... I was thinking "what if Ghost in the shell could come in our reality"?[/QUOTE] you thought wrong heretic

[QUOTE=ilikecorn;46664986]New antibiotics have always been in the works. It's just difficult to find something potent enough to kill the bacteria while not being potent enough to harm the user.[/QUOTE] This isn't true at all. There's no money in antibiotics due to the fact in most cases a person might take the drug once or twice then never need it again. It's also why they tend to be expensive. Getting a drug approved by the FDA can take up to ten years and cost million of dollars. The human testing phase tends to take up the bulk of that. On the other hand, because of the current issues with antibiotics and the lack of new ones, the FDA is trying to get a fast track thing going which would lessen the testing phase down to two years. I can't give exact numbers on things since I don't have my pharmacy practice notes in front of me, but if you're curious, I can dig them up.

One more reason to not go outside.

Humanity survived for a very long time without antibiotics. It won't be pretty, but I'm sure we can survive without them again. It'll be shit but I'd hardly call it apocalyptic. I wouldn't call most underdeveloped countries apocalyptic and they have no access to antibiotics.

[QUOTE=Empty_Shadow;46665864]Humanity survived for a very long time without antibiotics. It won't be pretty, but I'm sure we can survive without them again. It'll be shit but I'd hardly call it apocalyptic. I wouldn't call most underdeveloped countries apocalyptic and they have no access to antibiotics.[/QUOTE] It seems apocalyptic compared to alot of privileged and rich standards.

We will find a way or many of us will perish. The mother of invention is death by terrible and grotesque diseases

[QUOTE=Madtoker;46664622]Nothings going to change for a while since $$$[/QUOTE] doesn't make money if it doesn't work

[QUOTE=Mezzokoko;46665861]One more reason to not go outside.[/QUOTE] [t]http://ffmedia.ign.com/general/multimedia/bubbleboy1.jpg[/t] I shall live the rest of my life 500 feet in a nuclear underground facility in a bubble

Now, look to your left and to your right, the kid you see most constantly using hand sanitizer is the one who will have the roughest time. [editline]8th December 2014[/editline] Immuno-Enhanced Master Race [editline]8th December 2014[/editline] I've been training for this all my life.

Wasn't there recently an antiobiotic which the bacteria themselves use to break down their cell walls for reproducing, if we use that I can imagine becoming resistant will be hard. Won't they essentially need to stop using cell walls to become resistant?

Heh, I've never taken anti-biotics in my life. Just the occasional Panadol.

[QUOTE=uitham;46666083]Wasn't there recently an antiobiotic which the bacteria themselves use to break down their cell walls for reproducing, if we use that I can imagine becoming resistant will be hard. Won't they essentially need to stop using cell walls to become resistant?[/QUOTE] If it affects the structure of cell walls it may attack our own cells as well? Even if it doesn't it will still at least attack beneficial bacteria.

we have to find more natural antibiotics or we are all going to die sooner than you think

The last resort I see working even a little is the [URL="http://wyss.harvard.edu/viewpressrelease/166"]Biospleen[/URL], it's currently going through trials if I'm not mistaken.

[QUOTE=Ardosos;46665023]Maybe we can strategically infect people with "good" bacteria or something, compete with the "bad" bacteria for nutrients but are less harmful to people? Natural selection and such.[/QUOTE] As stupid as that sounds, they are actually working on infecting the bacteria with a genetically modified virus to kill them or even cooler, remove the antibiotic resistance from their DNA.

Look up bacteriaphages guise Had to write about antibioitic resistance in both my bio classes this year, tfw we are doomed

[QUOTE=Empty_Shadow;46665864]Humanity survived for a very long time without antibiotics. It won't be pretty, but I'm sure we can survive without them again. It'll be shit but I'd hardly call it apocalyptic. I wouldn't call most underdeveloped countries apocalyptic and they have no access to antibiotics.[/QUOTE] Pardon me fellow. I'm here to honk my bullshit horn at you. [IMG]http://www.ldolphin.org/poprecent.gif[/IMG] See this picture? This neat graph? Notice how the left hand side is really low, then the right hand side is really high. It indicates that a lot of people weren't surviving for various reasons. Sure, there are a lot of compounds in this case. Food, shelter, medical practices in general, but antibiotics sure as hell play a role in it. There is zero reason to be sure we can survive without something as crucial as Disease-B-Gone pills. The nice people who all caught black death and died in the medieval ages would have liked those.

[quote]Therein lies another problem, a lot of people when prescribed these antibiotics stop taking them when they feel better but that is literally the absolute worst thing you could do, since not all of the bacteria are dead yet and some could recover or return (giving the patient symptoms or leading to resistant bacteria). The complete treatment may be overkill, but its overkill for a good reason- all the bacteria need to be absolutely, positively, 100% obliterated. And cutting treatments short does not do that. [/quote] Holy christ. I was delusioned this whole time.

[QUOTE=Ardosos;46665023]Maybe we can strategically infect people with "good" bacteria or something, compete with the "bad" bacteria for nutrients but are less harmful to people? Natural selection and such.[/QUOTE] then we can televise live bacterial gladiator fights its perfect

[QUOTE=Str4fe;46665325]Humanity has taken hygiene and health way too far, relying on antibiotics and such, rather than our own immunity system. The immunity system is degrading and dying, soon we'll need medication to survive basic diseases.[/QUOTE] Relying on antibiotics isn't the problem, but abuse of antibiotics is the problem. Parents shouldn't be taking their children to get antibiotics for a minor ear infection which will just pass in a week or so for example. And people need to actually follow instructions. Though I do agree many people are too crazy with health, but that's just the nuts who use germ-ex on their hands every opportunity they get and are scared as fuck about everything. It's a minority.

[QUOTE=Zambies!;46664634]This isn't controlled enough for my liking. MRSA is real, obviously, but are these doctors able to get all the medications they need? Some hospitals I am aware of only have incredibly basic anti-biotics, and nothing that can defeat MRSA. Not sure of the situation there. Cleanliness is also a concern in some hospitals, which may make MRSA and MRSA-like infections more rampant in situations where they shouldn't. [editline]7th December 2014[/editline] ???[/QUOTE] He's right, pharmaceutical companies are pulling funding out of antibiotics because most fail trials, are super expensive to create and typically aren't worth trying to make now. So yeah we fucked ourselves, well done again humanity.

That's it, we're fucked. Everyone go home its only a matter of time now until bacteria kicks in your door and infects everyone you've ever known and loved. Thanks big pharma! Thanks doctors! Thanks oboingo!

[QUOTE=Crazy Ivan;46666714]Pardon me fellow. I'm here to honk my bullshit horn at you. [IMG]http://www.ldolphin.org/poprecent.gif[/IMG] See this picture? This neat graph? Notice how the left hand side is really low, then the right hand side is really high. It indicates that a lot of people weren't surviving for various reasons. Sure, there are a lot of compounds in this case. Food, shelter, medical practices in general, but antibiotics sure as hell play a role in it. There is zero reason to be sure we can survive without something as crucial as Disease-B-Gone pills. The nice people who all caught black death and died in the medieval ages would have liked those.[/QUOTE] How derp can you be. The reason there was a population explosion is because of the industrial age making it easier to mass produce food and making life easier in general. Nothing to do with antibiotics. This industrialization even kept the population skyrocketing through two horrific world wars when millions upon millions died. Anyone with half a braincell knows that 12 billion + is not a sustainable nor 'normal' population level but artificially maintained - its bound to be cut down to size at some point, through some measure. That doesn't mean that every last human will die. Not to say we shouldn't be researching more antibiotics, we should, but we should be mindful how fragile modern life is and how disconnected it is from actual reality especially in the west.

[QUOTE=Ardosos;46664959]Don't most antibiotics make you really sick? Or am I thinking of some other kind of treatment?[/QUOTE] You're thinking of chemotherapy. It makes you sick to kill the cancer. Antibiotics are given into the body so that the Immune system can adapt, it doesn't make you sick at all.