Difference between SetNW* or net.Broadcast?

Hi, what is best way to inform all players?
E.G.: We have 40 players and 2 from them are Infected?

Both will work, use the one you prefer/makes more sense.

Would I be mistaken in saying NWVars would be better, because they automatically sync to the client upon connecting, which would remove the need for him to manually Broadcast/send net message to the client about infected players?