I’m trying to use SetSequence in my SENT, but all it shows is the first frame of the animation. Does this need to be called every second, cause i haven’t. If not, what is the problem? I have nothing unusual, I just have a SetSequence on the ENT:Use() function.

no in your scripted entity set auto frame advance to true. Check out additional notes on this wiki

I did. No change.

Set the Sequence in a think hook.