SERVER Commands - what can I set during server start?

can I safely assume I can set all the server commands I see in the list like spawn.max_rate at Server start time?

if not, can we get a comprehensive list of server commands with examples and what can be only set in-game (RCON).

we are finding the rocks are getting scarce on our server with only 10 players. I added spawn.max_rate 2.4 and spawn_min_rate 1.0 but on a reboot they reset to .1 and 1.

When you set spawn.max_rate 2.4 did you remember to type server.writecfg ?

Doh! nope I did not!

Will that update the server config used at start up?
do you have a path to this file location?

thanks!